Abstract

Comment on

• Lactate influx through the endothelial cell monocarboxylate transporter MCT1 supports an NF-κB/IL-8 pathway that drives tumor angiogenesis.

  Végran F, Boidot R, Michiels C, Sonveaux P, Feron O.Végran F, et al.Cancer Res. 2011 Apr 1;71(7):2550-60. doi: 10.1158/0008-5472.CAN-10-2828. Epub 2011 Feb 7.Cancer Res. 2011.PMID:21300765

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Publication types

• Letter
• Comment

MeSH terms

• Breast Neoplasms / blood supply*
• Colorectal Neoplasms / blood supply*
• Humans
• Interleukin-8 / metabolism*
• Lactic Acid / pharmacokinetics*
• Monocarboxylic Acid Transporters / metabolism*
• NF-kappa B / metabolism*
• Symporters / metabolism*

Substances

• Interleukin-8
• Monocarboxylic Acid Transporters
• NF-kappa B
• Symporters
• Lactic Acid

Related information

• PubChem Compound
• PubChem Compound (MeSH Keyword)
• PubChem Substance

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