The antimicrobial sensitivity of Streptococcus mutans to nanoparticles of silver, zinc oxide, and gold
- PMID:18565800
- DOI: 10.1016/j.nano.2008.04.005
The antimicrobial sensitivity of Streptococcus mutans to nanoparticles of silver, zinc oxide, and gold
Abstract
Dental caries is a worldwide public health problem for which Streptococcus mutans has been identified as the possible infectious etiology. In recent years nanotechnology has permitted the development of new properties of materials. The objective of this study was to compare the bactericidal and bacteriostatic effects of nanoparticles of silver, zinc oxide, and gold on S. mutans. We used the liquid dilution method to find the minimum inhibitory concentrations (MICs) and with subcultures obtained the minimum bactericidal concentrations (MBCs). For silver the results showed an average MIC of 4.86 +/- 2.71 microg/mL and MBC of 6.25 microg/mL; for zinc the MIC was 500 +/- 306.18 muicrog/mL and MBC of 500 microg/mL; the gold nanoparticles demonstrated an effect only at an initial concentration of 197 mug/mL. We established a higher antimicrobial effect against S. mutans of silver nanoparticles at lower concentrations than gold or zinc, which would allow achieving important clinical effects with a reduced toxicity.
Similar articles
- [Evaluation of biocidal properties of silver nanoparticles against cariogenic bacteria].Pokrowiecki R, Zareba T, Mielczarek A, Opalińska A, Wojnarowicz J, Majkowski M, Lojkowski W, Tyski S.Pokrowiecki R, et al.Med Dosw Mikrobiol. 2013;65(3):197-206.Med Dosw Mikrobiol. 2013.PMID:24432559Polish.
- Bactericidal capacity of silver nanoparticles associated with Gantrez S-97 on Streptococcus mutans.Hernández-Sierra JF, Salas-López EK, Martínez-Gutiérrez F, Ruíz F, Pierdant-Pérez M, Mandeville P, Pozos-Guillén AJ.Hernández-Sierra JF, et al.J Clin Pediatr Dent. 2010 Winter;35(2):183-5. doi: 10.17796/jcpd.35.2.c61l421mj0655lgm.J Clin Pediatr Dent. 2010.PMID:21417121
- Silver nanoparticles in therapeutics: development of an antimicrobial gel formulation for topical use.Jain J, Arora S, Rajwade JM, Omray P, Khandelwal S, Paknikar KM.Jain J, et al.Mol Pharm. 2009 Sep-Oct;6(5):1388-401. doi: 10.1021/mp900056g.Mol Pharm. 2009.PMID:19473014
- Silver nanoparticles as a new generation of antimicrobials.Rai M, Yadav A, Gade A.Rai M, et al.Biotechnol Adv. 2009 Jan-Feb;27(1):76-83. doi: 10.1016/j.biotechadv.2008.09.002. Epub 2008 Sep 30.Biotechnol Adv. 2009.PMID:18854209Review.
- Antimicrobial activity of the metals and metal oxide nanoparticles.Dizaj SM, Lotfipour F, Barzegar-Jalali M, Zarrintan MH, Adibkia K.Dizaj SM, et al.Mater Sci Eng C Mater Biol Appl. 2014 Nov;44:278-84. doi: 10.1016/j.msec.2014.08.031. Epub 2014 Aug 16.Mater Sci Eng C Mater Biol Appl. 2014.PMID:25280707Review.
Cited by
- Therapeutic Use of Silver Nanoparticles in the Prevention and Arrest of Dental Caries.Butrón Téllez Girón C, Hernández Sierra JF, DeAlba-Montero I, Urbano Peña MLA, Ruiz F.Butrón Téllez Girón C, et al.Bioinorg Chem Appl. 2020 Aug 12;2020:8882930. doi: 10.1155/2020/8882930. eCollection 2020.Bioinorg Chem Appl. 2020.PMID:32855631Free PMC article.Review.
- A Randomized Controlled Trial Evaluating the Effectiveness of Nanosilver Fluoride in Arresting Dental Caries in School Children.Devi C, Chandrasekhar R, Vinay C, Uloopi KS, RojaRamya KS, Ramesh MV.Devi C, et al.Int J Clin Pediatr Dent. 2023 Sep-Oct;16(5):667-670. doi: 10.5005/jp-journals-10005-2604.Int J Clin Pediatr Dent. 2023.PMID:38162244Free PMC article.
- Preparation of a Novel Nanocomposite and Its Antibacterial Effectiveness againstEnterococcus faecalis-An In Vitro Evaluation.Jose J, Teja KV, Janani K, Alam MK, Khattak O, Salloum MG, Magar SS, Magar SP, Rajeshkumar S, Palanivelu A, Srivastava KC, Shrivastava D.Jose J, et al.Polymers (Basel). 2022 Apr 7;14(8):1499. doi: 10.3390/polym14081499.Polymers (Basel). 2022.PMID:35458249Free PMC article.
- Evaluation of the effect of antimicrobial nanoparticles on bond strength of orthodontic adhesives: A review article.Mirhashemi A, Jazi L.Mirhashemi A, et al.Dent Res J (Isfahan). 2021 Dec 10;18:110. eCollection 2021.Dent Res J (Isfahan). 2021.PMID:35265293Free PMC article.Review.
- Antibacterial activity and mechanism of silver nanoparticles against multidrug-resistantPseudomonas aeruginosa.Liao S, Zhang Y, Pan X, Zhu F, Jiang C, Liu Q, Cheng Z, Dai G, Wu G, Wang L, Chen L.Liao S, et al.Int J Nanomedicine. 2019 Feb 25;14:1469-1487. doi: 10.2147/IJN.S191340. eCollection 2019.Int J Nanomedicine. 2019.PMID:30880959Free PMC article.
Publication types
MeSH terms
Substances
Related information
LinkOut - more resources
Full Text Sources
Other Literature Sources