| Entry | |
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| Name | Demeclocycline (USP);
Demethylchlortetracycline (JAN) |
|---|
| Formula | C21H21ClN2O8
|
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| Exact mass | 464.0986
|
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| Mol weight | 464.85
|
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| Structure | 
|
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| Simcomp | |
|---|
| Source | Streptomyces aureofaciens [TAX: 1894] |
|---|
| Class | Antibacterial
DG01197 Tetracycline antibiotic
|
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| Remark | | Product (DG00396): | D00290<JP/US> |
|
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| Efficacy | Antibacterial, Protein biosynthesis inhibitor |
|---|
| Target | 30S ribosomal subunit |
|---|
| Pathway | |
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| Interaction | |
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| Structure map | |
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| Brite | Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
D DERMATOLOGICALS
D06 ANTIBIOTICS AND CHEMOTHERAPEUTICS FOR DERMATOLOGICAL USE
D06A ANTIBIOTICS FOR TOPICAL USE
D06AA Tetracycline and derivatives
D06AA01 Demeclocycline
D03680 Demeclocycline (USP)
J ANTIINFECTIVES FOR SYSTEMIC USE
J01 ANTIBACTERIALS FOR SYSTEMIC USE
J01A TETRACYCLINES
J01AA Tetracyclines
J01AA01 Demeclocycline
D03680 Demeclocycline (USP)
Risk category of Japanese OTC drugs [BR:br08312]
Second-class OTC drugs
Inorganic and organic chemicals
Demethylchlortetracycline
D03680 Demeclocycline (USP)
Drug groups [BR:br08330]
Antibacterial
DG01197 Tetracycline antibiotic
DG00396 Demeclocycline
D03680 Demeclocycline
Antimicrobials [BR:br08307]
Antibacterials
Protein biosynthesis inhibitor
Tetracycline
D03680 Demeclocycline (USP)
Drug groups [BR:br08330]
Antibacterial
DG01197 Tetracycline antibiotic
DG00396 Demeclocycline
Antimicrobials abbreviations [BR:br08327]
Antibacterials
Protein biosynthesis inhibitor
Tetracycline
DG00396 Demeclocycline
|
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| Other DBs | |
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| LinkDB | |
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| KCF data |
ATOM 32
1 C1y C 35.2619 -18.2923
2 C1z C 35.2503 -19.6742
3 C1y C 36.4630 -17.6043
4 C1x C 34.0550 -17.5927
5 C2y C 34.0550 -20.3739
6 C5x C 36.4455 -20.3739
7 O1a O 35.2503 -21.0676
8 C2y C 37.6582 -18.3040
9 N1c N 36.4689 -16.2050
10 C1y C 32.8481 -18.2923
11 C2y C 32.8481 -19.6859
12 O1a O 34.0609 -21.7790
13 C2y C 37.6524 -19.6917
14 O5x O 36.4398 -21.7731
15 O1a O 38.8710 -17.6103
16 C1a C 37.6875 -15.5113
17 C1a C 35.2619 -15.4996
18 C1y C 31.6355 -17.5927
19 C5x C 31.6472 -20.3913
20 C5a C 38.8535 -20.3913
21 C8y C 30.4286 -18.3040
22 O1a O 31.6355 -16.1234
23 C8y C 30.4344 -19.6976
24 O5x O 31.6590 -21.7906
25 N1a N 40.0720 -19.7033
26 O5a O 38.8477 -21.7963
27 C8y C 29.2158 -17.6043
28 C8y C 29.2333 -20.4030
29 C8x C 28.0030 -18.3157
30 X Cl 29.2100 -16.1992
31 C8x C 28.0147 -19.7149
32 O1a O 29.2450 -21.8080
BOND 35
1 1 2 1
2 1 3 1
3 1 4 1
4 2 5 1
5 2 6 1
6 2 7 1 #Down
7 3 8 1
8 3 9 1 #Down
9 4 10 1
10 5 11 2
11 5 12 1
12 6 13 1
13 6 14 2
14 8 15 1
15 9 16 1
16 9 17 1
17 10 18 1
18 11 19 1
19 13 20 1
20 18 21 1
21 18 22 1 #Up
22 19 23 1
23 19 24 2
24 20 25 1
25 20 26 2
26 21 27 1
27 23 28 1
28 27 29 2
29 27 30 1
30 28 31 2
31 28 32 1
32 8 13 2
33 10 11 1
34 21 23 2
35 29 31 1
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