| Entry | |
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| Name | Pipamperone (USAN/INN);
Floropipamide |
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| Formula | C21H30FN3O2
|
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| Exact mass | 375.2322
|
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| Mol weight | 375.48
|
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| Structure | 
|
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| Simcomp | |
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| Class | Neuropsychiatric agent
DG01478 Dopamine antagonist
DG01474 Dopamine D2-receptor antagonist
DG03200 Antipsychotic agent
DG01940 Butyrophenone derivative
|
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| Remark | | Product (DG00889): | D01482<JP> |
|
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| Efficacy | Antipsychotic, Dopamine D2 receptor antagonist |
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| Comment | Butyrophenone derivative
|
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| Target | |
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| Pathway | | hsa04080 | Neuroactive ligand-receptor interaction |
|
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| Interaction | |
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| Structure map | | map07031 | Antipsychotics - butyrophenones |
|
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| Brite | Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
N NERVOUS SYSTEM
N05 PSYCHOLEPTICS
N05A ANTIPSYCHOTICS
N05AD Butyrophenone derivatives
N05AD05 Pipamperone
D02622 Pipamperone (USAN/INN)
Drug groups [BR:br08330]
Neuropsychiatric agent
DG01478 Dopamine antagonist
DG01474 Dopamine D2-receptor antagonist
DG00889 Pipamperone
D02622 Pipamperone
DG03200 Antipsychotic agent
DG01940 Butyrophenone derivative
DG00889 Pipamperone
D02622 Pipamperone
Target-based classification of drugs [BR:br08310]
G Protein-coupled receptors
Rhodopsin family
Dopamine
DRD2
D02622 Pipamperone (USAN/INN)
Drug groups [BR:br08330]
Neuropsychiatric agent
DG01478 Dopamine antagonist
DG01474 Dopamine D2-receptor antagonist
DG00889 Pipamperone
DG03200 Antipsychotic agent
DG01940 Butyrophenone derivative
DG00889 Pipamperone
|
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| Other DBs | |
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| LinkDB | |
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| KCF data |
ATOM 27
1 C1z C 26.3900 -16.0300
2 C1x C 25.2000 -15.3300
3 C1x C 23.9400 -16.0300
4 N1y N 23.9400 -17.4300
5 C1x C 25.2000 -18.1300
6 C1x C 26.3900 -17.4300
7 C1b C 22.7500 -18.1300
8 C1b C 21.5600 -17.4300
9 C1b C 20.3000 -18.1300
10 C5a C 19.1100 -17.4300
11 C8y C 17.9200 -18.1300
12 O5a O 19.1100 -16.0300
13 C8x C 16.7300 -17.4300
14 C8x C 15.4700 -18.1300
15 C8y C 15.4700 -19.5300
16 C8x C 16.7300 -20.2300
17 C8x C 17.9200 -19.5300
18 X F 14.2800 -20.1600
19 N1y N 27.5800 -15.3300
20 C1x C 28.8400 -16.0300
21 C1x C 30.0300 -15.3300
22 C1x C 30.0300 -13.9300
23 C1x C 28.8400 -13.2300
24 C1x C 27.5800 -13.9300
25 C5a C 27.0900 -17.2200
26 N1a N 28.4900 -17.2200
27 O5a O 26.3900 -18.4100
BOND 29
1 6 1 1
2 4 7 1
3 11 13 2
4 13 14 1
5 14 15 2
6 15 16 1
7 16 17 2
8 17 11 1
9 15 18 1
10 7 8 1
11 1 19 1
12 8 9 1
13 1 2 1
14 9 10 1
15 2 3 1
16 19 20 1
17 20 21 1
18 21 22 1
19 22 23 1
20 23 24 1
21 24 19 1
22 10 11 1
23 3 4 1
24 10 12 2
25 4 5 1
26 5 6 1
27 25 26 1
28 25 1 1
29 25 27 2
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