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Galr3Gene Detail
Summary
  • Symbol
    Galr3
  • Name
    galanin receptor 3
  • Synonyms
    Galnr3
  • Feature Type
    protein coding gene
  • IDs
    MGI:1329003
    NCBI Gene:14429
  • Alliance
Location &
Maps
more
  • Sequence Map
    Chr15:78926085-78927758 bp, + strand
    From NCBI annotation of GRCm39
  • View this region inJBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 15, 37.70 cM
  • Mapping Data
    4 experiments
Strain
Comparison
more
  • SNPs within 2kb
    134from dbSNP Build 142
  • Strain Annotations
    1
For selected strains:
StrainGene Model IDFeature TypeCoordinatesSelect Strains
C57BL/6JMGI_C57BL6J_1329003
protein coding geneChr15:78926085-78927758 (+)
129S1/SvImJno annotation
A/Jno annotation
AKR/Jno annotation
BALB/cJno annotation
C3H/HeJno annotation
C57BL/6NJno annotation
CAROLI/EiJno annotation
CAST/EiJno annotation
CBA/Jno annotation
DBA/2Jno annotation
FVB/NJno annotation
LP/Jno annotation
NOD/ShiLtJno annotation
NZO/HlLtJno annotation
PWK/PhJno annotation
SPRET/EiJno annotation
WSB/EiJno annotation



Homology
more
  • Human Ortholog
    GALR3, galanin receptor 3
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    GALR3,galanin receptor 3
  • Links
    NCBI Gene ID:8484
    UniProt:O60755

  • Chr Location
    22q13.1; chr22:37823382-37825485(+)  GRCh38
Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    10 phenotypesfrom 1 allelein 2 genetic backgrounds
    33 phenotype references
Phenotype Overview

Phenotype Overview
Blue squares indicate phenotypes directly attributed to mutations/alleles of this gene.
adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
  • All Mutations and Alleles
  • Chemically induced (other)
  • Endonuclease-mediated
  • Radiation induced
  • Targeted
  • Genomic Mutations
    3 involving Galr3
  • Incidental Mutations
  • Find Mice (IMSR)
Mice homozygous for a null allele exhibit increased anxiety-like behavior and abnormal social investigation.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

Expression Overview
GXD's primary emphasis is on endogenous gene expression during development. Click on grid cells to view annotations.
  • Blue cells = expressed in wild-type.
    Gray triangles = other expression annotations only
    (e.g. absence of expression or data from mutants).
early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • cDNA Data
  • Literature Summary
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic14429NCBI Gene Model |MGI Sequence Detail1674C57BL/6J± kb
transcriptNM_015738RefSeq |MGI Sequence Detail1245Not Specified 
polypeptideO88853UniProt |EBI |MGI Sequence Detail370Not Applicable 
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic4
    cDNA4

    Microarray probesets3
References
more
  • Summaries
    All68
    Developmental Gene Expression1
    Diseases1
    Gene Ontology11
    Phenotypes33
  • Earliest
    J:7688 Lane PW, et al., Association of megacolon with a new dominant spotting gene (Dom) in the mouse. J Hered. 1984 Nov-Dec;75(6):435-9
  • Latest
    J:372809 Brunner SM, et al., Impact of galanin receptors 2 and 3 double-knockout on neuroinflammation and functional recovery following traumatic brain injury. Peptides. 2025 Sep;191:171415
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.		 last database update
01/20/2026
MGI 6.24		The Jackson Laboratory
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