| Name | Population | Latitude/Longitude |
|---|
| 1 | Havana  , Havana | 2,163,824 | 23.133 / -82.383 |
| 2 | Santiago de Cuba , Santiago de Cuba Province | 555,865 | 20.023 / -75.822 |
| 3 | Camagüey , Camagüey | 347,562 | 21.381 / -77.917 |
| 4 | Holguín , Holguín Province | 319,102 | 20.887 / -76.263 |
| 5 | Guantánamo , Guantánamo Province | 272,801 | 20.144 / -75.209 |
| 6 | Santa Clara , Villa Clara Province | 250,512 | 22.407 / -79.966 |
| 7 | Arroyo Naranjo, Havana | 210,053 | 23.038 / -82.377 |
| 8 | Las Tunas , Las Tunas Province | 203,684 | 20.961 / -76.952 |
| 9 | Bayamo , Granma Province | 192,632 | 20.374 / -76.643 |
| 10 | Pinar del Río , Pinar del Río | 186,990 | 22.416 / -83.697 |
| 11 | Cienfuegos, Cienfuegos Province | 186,644 | 22.147 / -80.448 |
| 12 | Fontanar, Havana | 178,601 | 23.024 / -82.408 |
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