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Human(GRCh38.p14)

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Transcript: ENST00000418331.7PTPRJ-201

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Description

protein tyrosine phosphatase receptor type J [Source:HGNC Symbol;Acc:HGNC:9673]

Gene Synonyms

CD148, DEP1, HPTPETA

Location
About this transcript

This transcript has25 exons, is annotated with64 domains and features, is associated with78754 variant alleles and maps to862 oligo probes.

Gene
Transcript IDNamebpProteinTranslation IDBiotypeCCDSUniProt MatchRefSeq MatchFlags
ENST00000418331.7PTPRJ-20178451337aaENSP00000400010.2
 
Gene/transcipt that contains an open reading frame (ORF).Protein coding
CCDS7945Q12913-1NM_002843.4The Matched Annotation from NCBI and EMBL-EBI is a collaboration between Ensembl/GENCODE and RefSeq. The MANE Select is a default transcript per human gene that is representative of biology, well-supported, expressed and highly-conserved. This transcript set matches GRCh38 and is 100% identical between RefSeq and Ensembl/GENCODE for 5' UTR, CDS, splicing and 3'UTR.MANE SelectA single transcript chosen for a gene which is the most conserved, most highly expressed, has the longest coding sequence and is represented in other key resources, such as NCBI and UniProt. This is defined in detail on http://www.ensembl.org/info/genome/genebuild/canonical.htmlEnsembl CanonicalGENCODE Primary represents a minimal set that contains MANE Select, MANE Plus Clinical and Ensembl Canonical transcripts and transcripts containing any conserved exons and common alternative splicing events (including exons skips) that are absent from the MANE and Ensembl Canonical transcripts for protein-coding genes. Other biotypes will have the GENCODE Primary flag added to the Ensembl Canonical transcript and for lncRNA genes only this will be the transcripts with the longest genomic span.GENCODE PrimaryA subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic

APPRIS P2: Where the APPRIS core modules are unable to choose a clear principal variant (approximately 25% of human protein coding genes), the database chooses two or more of the CDS variants as "candidates" to be the principal variant.

APPRIS is a system to annotate alternatively spliced transcripts based on a range of computational methods to identify the most functionally important transcript(s) of a gene.

APPRIS P2

TSL 1: A transcript where all splice junctions are supported by at least one non-suspect mRNA.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users, based on the type and quality of the alignments used to annotate the transcript.

TSL:1
ENST00000698881.1PTPRJ-20779791451aaENSP00000514003.1
 
Gene/transcipt that contains an open reading frame (ORF).Protein coding
A0A8V8TP51-A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic

APPRIS ALT2: For genes in which the APPRIS core modules are unable to choose a clear principal isoform, the ALT1 is the candidate transcript(s) models that appear to be conserved in fewer than three tested species.

APPRIS is a system to annotate alternatively spliced transcripts based on a range of computational methods to identify the most functionally important transcript(s) of a gene.

APPRIS ALT2
ENST00000440289.6PTPRJ-2023158539aaENSP00000409733.2
 
Gene/transcipt that contains an open reading frame (ORF).Protein coding
CCDS44596Q12913-2-A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic

TSL 1: A transcript where all splice junctions are supported by at least one non-suspect mRNA.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users, based on the type and quality of the alignments used to annotate the transcript.

TSL:1
ENST00000527952.1PTPRJ-205626146aaENSP00000435618.1
 
Gene/transcipt that contains an open reading frame (ORF).Protein coding
E9PJ83-

TSL 5: A transcript where no single transcript supports the model structure.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users, based on the type and quality of the alignments used to annotate the transcript.

TSL:5
3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete
ENST00000534219.5PTPRJ-206546120aaENSP00000432686.1
 
Gene/transcipt that contains an open reading frame (ORF).Protein coding
E9PPH3-

TSL 3: A transcript where the only support is from a single EST

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users, based on the type and quality of the alignments used to annotate the transcript.

TSL:3
3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete
ENST00000526550.1PTPRJ-203571No protein-
 
Alternatively spliced transcript of a protein coding gene for which we cannot define a CDS.Protein coding CDS not defined
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TSL 4: A transcript where the best supporting EST is flagged as suspect

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users, based on the type and quality of the alignments used to annotate the transcript.

TSL:4
ENST00000527026.1PTPRJ-204555No protein-
 
An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron
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TSL 4: A transcript where the best supporting EST is flagged as suspect

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users, based on the type and quality of the alignments used to annotate the transcript.

TSL:4

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Protein domains for ENSP00000400010.2

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Ensembl release 113 - October 2024 ©EMBL-EBIEMBL-EBI
http://asia.ensembl.org

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