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Transcript: ENST00000680807.1AATF-220

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Description

apoptosis antagonizing transcription factor [Source:HGNC Symbol;Acc:HGNC:19235]

Gene Synonyms

BFR2, CHE-1, CHE1, DED

Location
About this transcript

This transcript has9 exons and maps to297 oligo probes.

Gene
Transcript IDNamebpProteinTranslation IDBiotypeCCDSUniProt MatchRefSeq MatchFlags
ENST00000619387.5AATF-2082062560aaENSP00000477848.1
 
Gene/transcipt that contains an open reading frame (ORF).Protein coding
CCDS32632Q9NY61NM_012138.4The Matched Annotation from NCBI and EMBL-EBI is a collaboration between Ensembl/GENCODE and RefSeq. The MANE Select is a default transcript per human gene that is representative of biology, well-supported, expressed and highly-conserved. This transcript set matches GRCh38 and is 100% identical between RefSeq and Ensembl/GENCODE for 5' UTR, CDS, splicing and 3'UTR.MANE SelectA single transcript chosen for a gene which is the most conserved, most highly expressed, has the longest coding sequence and is represented in other key resources, such as NCBI and UniProt. This is defined in detail on http://www.ensembl.org/info/genome/genebuild/canonical.htmlEnsembl CanonicalGENCODE Primary represents a minimal set that contains MANE Select, MANE Plus Clinical and Ensembl Canonical transcripts and transcripts containing any conserved exons and common alternative splicing events (including exons skips) that are absent from the MANE and Ensembl Canonical transcripts for protein-coding genes. Other biotypes will have the GENCODE Primary flag added to the Ensembl Canonical transcript and for lncRNA genes only this will be the transcripts with the longest genomic span.GENCODE PrimaryA subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic

APPRIS P2: Where the APPRIS core modules are unable to choose a clear principal variant (approximately 25% of human protein coding genes), the database chooses two or more of the CDS variants as "candidates" to be the principal variant.

APPRIS is a system to annotate alternatively spliced transcripts based on a range of computational methods to identify the most functionally important transcript(s) of a gene.

APPRIS P2

TSL 1: A transcript where all splice junctions are supported by at least one non-suspect mRNA.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users, based on the type and quality of the alignments used to annotate the transcript.

TSL:1
ENST00000679881.1AATF-2122712397aaENSP00000504972.1
 
Gene/transcipt that contains an open reading frame (ORF).Protein coding
A0A7P0Z4P2-A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic

APPRIS ALT2: For genes in which the APPRIS core modules are unable to choose a clear principal isoform, the ALT1 is the candidate transcript(s) models that appear to be conserved in fewer than three tested species.

APPRIS is a system to annotate alternatively spliced transcripts based on a range of computational methods to identify the most functionally important transcript(s) of a gene.

APPRIS ALT2
ENST00000680782.1AATF-2192629373aaENSP00000506681.1
 
Gene/transcipt that contains an open reading frame (ORF).Protein coding
A0A7P0TBI0-A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic
ENST00000681062.1AATF-2212060397aaENSP00000506608.1
 
Gene/transcipt that contains an open reading frame (ORF).Protein coding
A0A7P0Z4P2-A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic

APPRIS ALT2: For genes in which the APPRIS core modules are unable to choose a clear principal isoform, the ALT1 is the candidate transcript(s) models that appear to be conserved in fewer than three tested species.

APPRIS is a system to annotate alternatively spliced transcripts based on a range of computational methods to identify the most functionally important transcript(s) of a gene.

APPRIS ALT2
ENST00000680340.1AATF-2162018536aaENSP00000506264.1
 
Gene/transcipt that contains an open reading frame (ORF).Protein coding
CCDS92291A0A7P0TAR0-A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic
ENST00000679997.1AATF-2142007540aaENSP00000505070.1
 
Gene/transcipt that contains an open reading frame (ORF).Protein coding
A0A7P0T868-GENCODE Primary represents a minimal set that contains MANE Select, MANE Plus Clinical and Ensembl Canonical transcripts and transcripts containing any conserved exons and common alternative splicing events (including exons skips) that are absent from the MANE and Ensembl Canonical transcripts for protein-coding genes. Other biotypes will have the GENCODE Primary flag added to the Ensembl Canonical transcript and for lncRNA genes only this will be the transcripts with the longest genomic span.GENCODE PrimaryA subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic
ENST00000616434.2AATF-2061940514aaENSP00000477881.2
 
Gene/transcipt that contains an open reading frame (ORF).Protein coding
A0A087WTH8-A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic

TSL 3: A transcript where the only support is from a single EST

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users, based on the type and quality of the alignments used to annotate the transcript.

TSL:3
ENST00000610798.4AATF-201601154aaENSP00000480472.1
 
Gene/transcipt that contains an open reading frame (ORF).Protein coding
A0A087WWS8-

TSL 2: A transcript where the best supporting mRNA is flagged as suspect or the support is from multiple ESTs

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users, based on the type and quality of the alignments used to annotate the transcript.

TSL:25' truncation in transcript evidence prevents annotation of the start of the CDS.CDS 5' incomplete
ENST00000680330.1AATF-2152446474aaENSP00000506539.1
 
Nonsense mediated decay
A0A7P0Z4N2--
ENST00000680356.1AATF-2172076503aaENSP00000505146.1
 
Nonsense mediated decay
A0A7P0Z434--
ENST00000680579.1AATF-2181963288aaENSP00000506655.1
 
Nonsense mediated decay
A0A7P0TBG4--
ENST00000613840.1AATF-20264855aaENSP00000479926.1
 
Nonsense mediated decay
A0A087WW41-

TSL 2: A transcript where the best supporting mRNA is flagged as suspect or the support is from multiple ESTs

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users, based on the type and quality of the alignments used to annotate the transcript.

TSL:2
ENST00000679508.1AATF-2101720No protein-
 
Alternatively spliced transcript of a protein coding gene for which we cannot define a CDS.Protein coding CDS not defined
---
ENST00000616062.1AATF-204507No protein-
 
Alternatively spliced transcript of a protein coding gene for which we cannot define a CDS.Protein coding CDS not defined
--

TSL 5: A transcript where no single transcript supports the model structure.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users, based on the type and quality of the alignments used to annotate the transcript.

TSL:5
ENST00000622432.1AATF-209376No protein-
 
Alternatively spliced transcript of a protein coding gene for which we cannot define a CDS.Protein coding CDS not defined
--

TSL 2: A transcript where the best supporting mRNA is flagged as suspect or the support is from multiple ESTs

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users, based on the type and quality of the alignments used to annotate the transcript.

TSL:2
ENST00000680807.1AATF-2204050No protein-
 
An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron
---
ENST00000679985.1AATF-2133021No protein-
 
An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron
---
ENST00000679600.1AATF-2112649No protein-
 
An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron
---
ENST00000681800.1AATF-2232598No protein-
 
An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron
---
ENST00000615319.1AATF-2032044No protein-
 
An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron
--

TSL NA: A transcript that was not analysed for TSL.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users, based on the type and quality of the alignments used to annotate the transcript.

TSL:NA
ENST00000681070.1AATF-2221390No protein-
 
An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron
---
ENST00000617141.1AATF-207586No protein-
 
An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron
--

TSL 2: A transcript where the best supporting mRNA is flagged as suspect or the support is from multiple ESTs

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users, based on the type and quality of the alignments used to annotate the transcript.

TSL:2
ENST00000616392.1AATF-205474No protein-
 
An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron
--

TSL 2: A transcript where the best supporting mRNA is flagged as suspect or the support is from multiple ESTs

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users, based on the type and quality of the alignments used to annotate the transcript.

TSL:2

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Statistics

Exons: 9,Coding exons: 0,Transcript length: 4,050 bps,

Version

ENST00000680807.1

Type

Retained intron

Annotation Method

Manual annotation (determined on a case-by-case basis) from the Havana project.

Annotation Attributes

RNA-Seq supported only [Definitions]

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Ensembl release 113 - October 2024 ©EMBL-EBIEMBL-EBI
http://asia.ensembl.org

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