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Transcript: ENST00000549510.1SOCS2-208

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Description

suppressor of cytokine signaling 2 [Source:HGNC Symbol;Acc:HGNC:19382]

Gene Synonyms

CIS2, CISH2, SOCS-2, SSI-2, SSI2, STATI2

Location
About this transcript

This transcript has2 exons, is annotated with7 domains and features and maps to134 oligo probes.

Gene
Transcript IDNamebpProteinTranslation IDBiotypeCCDSUniProt MatchRefSeq MatchFlags
ENST00000551556.2SOCS2-2102386198aaENSP00000449227.1
 
Gene/transcipt that contains an open reading frame (ORF).Protein coding
CCDS9047O14508NM_001270471.2The Matched Annotation from NCBI and EMBL-EBI is a collaboration between Ensembl/GENCODE and RefSeq. The MANE Select is a default transcript per human gene that is representative of biology, well-supported, expressed and highly-conserved. This transcript set matches GRCh38 and is 100% identical between RefSeq and Ensembl/GENCODE for 5' UTR, CDS, splicing and 3'UTR.MANE SelectA single transcript chosen for a gene which is the most conserved, most highly expressed, has the longest coding sequence and is represented in other key resources, such as NCBI and UniProt. This is defined in detail on http://www.ensembl.org/info/genome/genebuild/canonical.htmlEnsembl CanonicalGENCODE Primary represents a minimal set that contains MANE Select, MANE Plus Clinical and Ensembl Canonical transcripts and transcripts containing any conserved exons and common alternative splicing events (including exons skips) that are absent from the MANE and Ensembl Canonical transcripts for protein-coding genes. Other biotypes will have the GENCODE Primary flag added to the Ensembl Canonical transcript and for lncRNA genes only this will be the transcripts with the longest genomic span.GENCODE PrimaryA subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic

APPRIS P1: Transcript(s) expected to code for the main functional isoform based solely on the core modules in the APPRIS.

APPRIS is a system to annotate alternatively spliced transcripts based on a range of computational methods to identify the most functionally important transcript(s) of a gene.

APPRIS P1

TSL 1: A transcript where all splice junctions are supported by at least one non-suspect mRNA.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users, based on the type and quality of the alignments used to annotate the transcript.

TSL:1
ENST00000548537.1SOCS2-2053733102aaENSP00000448709.1
 
Gene/transcipt that contains an open reading frame (ORF).Protein coding
F8VS53-GENCODE Primary represents a minimal set that contains MANE Select, MANE Plus Clinical and Ensembl Canonical transcripts and transcripts containing any conserved exons and common alternative splicing events (including exons skips) that are absent from the MANE and Ensembl Canonical transcripts for protein-coding genes. Other biotypes will have the GENCODE Primary flag added to the Ensembl Canonical transcript and for lncRNA genes only this will be the transcripts with the longest genomic span.GENCODE PrimaryA subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic

TSL 2: A transcript where the best supporting mRNA is flagged as suspect or the support is from multiple ESTs

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users, based on the type and quality of the alignments used to annotate the transcript.

TSL:2
ENST00000622746.4SOCS2-2122881198aaENSP00000481249.1
 
Gene/transcipt that contains an open reading frame (ORF).Protein coding
CCDS9047O14508-A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic

APPRIS P1: Transcript(s) expected to code for the main functional isoform based solely on the core modules in the APPRIS.

APPRIS is a system to annotate alternatively spliced transcripts based on a range of computational methods to identify the most functionally important transcript(s) of a gene.

APPRIS P1

TSL 3: A transcript where the only support is from a single EST

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users, based on the type and quality of the alignments used to annotate the transcript.

TSL:3
ENST00000340600.6SOCS2-2012761198aaENSP00000339428.2
 
Gene/transcipt that contains an open reading frame (ORF).Protein coding
CCDS9047O14508-A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic

APPRIS P1: Transcript(s) expected to code for the main functional isoform based solely on the core modules in the APPRIS.

APPRIS is a system to annotate alternatively spliced transcripts based on a range of computational methods to identify the most functionally important transcript(s) of a gene.

APPRIS P1

TSL 1: A transcript where all splice junctions are supported by at least one non-suspect mRNA.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users, based on the type and quality of the alignments used to annotate the transcript.

TSL:1
ENST00000549122.5SOCS2-2062391198aaENSP00000447161.1
 
Gene/transcipt that contains an open reading frame (ORF).Protein coding
CCDS9047O14508-GENCODE Primary represents a minimal set that contains MANE Select, MANE Plus Clinical and Ensembl Canonical transcripts and transcripts containing any conserved exons and common alternative splicing events (including exons skips) that are absent from the MANE and Ensembl Canonical transcripts for protein-coding genes. Other biotypes will have the GENCODE Primary flag added to the Ensembl Canonical transcript and for lncRNA genes only this will be the transcripts with the longest genomic span.GENCODE PrimaryA subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic

APPRIS P1: Transcript(s) expected to code for the main functional isoform based solely on the core modules in the APPRIS.

APPRIS is a system to annotate alternatively spliced transcripts based on a range of computational methods to identify the most functionally important transcript(s) of a gene.

APPRIS P1

TSL 1: A transcript where all splice junctions are supported by at least one non-suspect mRNA.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users, based on the type and quality of the alignments used to annotate the transcript.

TSL:1
ENST00000549206.5SOCS2-2072072198aaENSP00000448815.1
 
Gene/transcipt that contains an open reading frame (ORF).Protein coding
CCDS9047O14508-A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic

APPRIS P1: Transcript(s) expected to code for the main functional isoform based solely on the core modules in the APPRIS.

APPRIS is a system to annotate alternatively spliced transcripts based on a range of computational methods to identify the most functionally important transcript(s) of a gene.

APPRIS P1

TSL 3: A transcript where the only support is from a single EST

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users, based on the type and quality of the alignments used to annotate the transcript.

TSL:3
ENST00000536696.6SOCS2-2021065198aaENSP00000442898.2
 
Gene/transcipt that contains an open reading frame (ORF).Protein coding
CCDS9047O14508-GENCODE Primary represents a minimal set that contains MANE Select, MANE Plus Clinical and Ensembl Canonical transcripts and transcripts containing any conserved exons and common alternative splicing events (including exons skips) that are absent from the MANE and Ensembl Canonical transcripts for protein-coding genes. Other biotypes will have the GENCODE Primary flag added to the Ensembl Canonical transcript and for lncRNA genes only this will be the transcripts with the longest genomic span.GENCODE PrimaryA subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic

APPRIS P1: Transcript(s) expected to code for the main functional isoform based solely on the core modules in the APPRIS.

APPRIS is a system to annotate alternatively spliced transcripts based on a range of computational methods to identify the most functionally important transcript(s) of a gene.

APPRIS P1

TSL 2: A transcript where the best supporting mRNA is flagged as suspect or the support is from multiple ESTs

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users, based on the type and quality of the alignments used to annotate the transcript.

TSL:2
ENST00000549887.1SOCS2-209984161aaENSP00000448611.1
 
Gene/transcipt that contains an open reading frame (ORF).Protein coding
F8VRV3-

TSL 3: A transcript where the only support is from a single EST

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users, based on the type and quality of the alignments used to annotate the transcript.

TSL:3
3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete
ENST00000548091.5SOCS2-204744142aaENSP00000447902.1
 
Gene/transcipt that contains an open reading frame (ORF).Protein coding
F8VU91-

TSL 3: A transcript where the only support is from a single EST

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users, based on the type and quality of the alignments used to annotate the transcript.

TSL:3
3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete
ENST00000551883.1SOCS2-211719116aaENSP00000474805.1
 
Gene/transcipt that contains an open reading frame (ORF).Protein coding
S4R3W1-

TSL 2: A transcript where the best supporting mRNA is flagged as suspect or the support is from multiple ESTs

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users, based on the type and quality of the alignments used to annotate the transcript.

TSL:2
5' truncation in transcript evidence prevents annotation of the start of the CDS.CDS 5' incomplete
ENST00000549510.1SOCS2-20858146aaENSP00000474888.1
 
Gene/transcipt that contains an open reading frame (ORF).Protein coding
S4R3Z4-

TSL 2: A transcript where the best supporting mRNA is flagged as suspect or the support is from multiple ESTs

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users, based on the type and quality of the alignments used to annotate the transcript.

TSL:2
5' truncation in transcript evidence prevents annotation of the start of the CDS.CDS 5' incomplete
ENST00000547229.1SOCS2-2034622aaENSP00000473902.1
 
Gene/transcipt that contains an open reading frame (ORF).Protein coding
--

TSL 2: A transcript where the best supporting mRNA is flagged as suspect or the support is from multiple ESTs

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users, based on the type and quality of the alignments used to annotate the transcript.

TSL:2
3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete

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Statistics

Exons: 2,Coding exons: 2,Transcript length: 581 bps,Translation length: 46 residues

Transcript Support Level (TSL)

TSL:2

Incomplete CDS

5' truncation in transcript evidence prevents annotation of the start of the CDS.CDS 5' incomplete

Version

ENST00000549510.1

Type

Protein coding

Annotation Method

Manual annotation (determined on a case-by-case basis) from the Havana project.

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Ensembl release 113 - October 2024 ©EMBL-EBIEMBL-EBI
http://asia.ensembl.org

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