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HDBR
HDBR
emailenquiries@hdbr.org

The MRC-Wellcome Trust Human Developmental Biology Resource (HDBR) is organised from two sites: the Institute of Genetic Medicine, Newcastle, and the Institute of Child Health, London. The HDBR is an ongoing collection of human embryonic and fetal material ranging from 3 to 20 weeks of development.

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Latest News
Sustainable HDBRMay 2, 2025HDBR in the Journal of Anatomy Top 10March 20, 2025Newcastle University Biosciences Image of the Year 2024December 16, 2024HDBR Out and AboutDecember 2, 2024The development of the urogenital systemDecember 2, 2024The methylomic landscape of human articular cartilage development contains epigenetic signatures of ...November 26, 2024Relating normal human cardiac development to the anatomical findings in the congenitally malformed h...November 21, 2024A human genome editing–based MLL::AF4 ALL model recapitulates key cellular and molecular leukemoge...September 4, 2024Increased dosage of DYRK1A leads to congenital heart defects in a mouse model of Down syndromeAugust 22, 2024Early human lung immune cell development and its role in epithelial cell fateAugust 22, 2024

About the HDBR

The HDBR was established in 1999 in line with the ethical guidelines laid out in the Polkinghorne Report (Review of the Guidance on the Research Use of Fetuses and Fetal Material, 1989). More recently, we have been licensed as a tissue bank at each site by the Human Tissue Authority...

HDBR Atlas

The HDBR Atlas is a unique resource which aims to facilitate the understanding of human development. 3D models provide a framework in which anatomical structures are defined and gene expression data is mapped. The Atlas also hosts annotated high resolution histology sections.

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Limitations of working with human materialFixation and sectioningH&E protocolExtraction of RNA and DNA
HDBR

Enabling human development research and understanding of congenital disease

General Information  Information for researchers and how to apply  

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