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Smoother is an interactive analysis and visualization software for contact mapping data.This repository, libSmoother, contains the backend C++ library that powers Smoother.The library takes care of all the time-sensitive computations.It is written in C++17 and offers seamless integration with Python 3.

create & activate a new environment (optional)

conda create -y -n smoother python=3.9conda activate smoother

Install libSmoother (and all requirements) using pip. LibSmoother runs under Windows, Linux, and MacOS.

pip install libbiosmoother

Download 2 example smoother indices.

wget https://syncandshare.lrz.de/getlink/fi4kLPLjRjMTbRnij7PtyB/t_brucei_hi_c.smoother_index.zip#wget https://syncandshare.lrz.de/getlink/fiMo5Zsj8baXjXpzD8Whic/m_musculus_radicl_seq.smoother_index.zipconda install unzipunzip t_brucei_hi_c.smoother_index.zip#unzip m_musculus_radicl_seq.smoother_index.zip

Export a picture from one of the indices

libbiosmoother export t_brucei_hi_c-c -f png#libbiosmoother export m_musculus_radicl_seq -f png

SinceSmoother and libSmoother are designed as one package, they share documentation.Hence, for more information and in-depth instructions, check outSmoother's manual.

If you use Smoother in your research, please cite:@todo