1720: Edward Phillips (author) and John Kerſey (editor),The New World of Words : or, Univerſal Engliſh Dictionary,PU–PY (7th edition):
Pylorus, the Keeper of a Gate, a Porter. InAnatomy, the lower Orifice or Mouth of the Stomach, by which the Meat is let into the Entrails, theMaw-gut : It is alſo call’dJanitor inLatin.