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ZNF41

From Wikipedia, the free encyclopedia
Protein-coding gene in the species Homo sapiens
ZNF41
Identifiers
AliasesZNF41, MRX89, zinc finger protein 41
External IDsOMIM:314995;HomoloGene:133263;GeneCards:ZNF41;OMA:ZNF41 - orthologs
Gene location (Human)
X chromosome (human)
Chr.X chromosome (human)[1]
X chromosome (human)
Genomic location for ZNF41
Genomic location for ZNF41
BandXp11.3Start47,445,178bp[1]
End47,483,222bp[1]
RNA expression pattern
Bgee
HumanMouse (ortholog)
Top expressed in
  • muscle of leg

  • gonad

  • gastrocnemius muscle

  • muscle of thigh

  • islet of Langerhans

  • apex of heart

  • rectum

  • ganglionic eminence

  • ventricular zone

  • white blood cell
    n/a
More reference expression data
BioGPS
More reference expression data
Gene ontology
Molecular function
Cellular component
Biological process
Sources:Amigo /QuickGO
Orthologs
SpeciesHumanMouse
Entrez

7592

n/a

Ensembl

ENSG00000147124

n/a

UniProt

P51814

n/a

RefSeq (mRNA)
NM_007130
NM_153380
NM_001324139
NM_001324140
NM_001324141

NM_001324142
NM_001324143
NM_001324144
NM_001324145
NM_001324147
NM_001324148
NM_001324149
NM_001324150
NM_001324151
NM_001324152
NM_001324153
NM_001324154
NM_001324155
NM_001324156
NM_001324157

n/a

RefSeq (protein)
NP_001311068
NP_001311069
NP_001311070
NP_001311071
NP_001311072

NP_001311073
NP_001311074
NP_001311076
NP_001311077
NP_001311078
NP_001311079
NP_001311080
NP_001311081
NP_001311082
NP_001311083
NP_001311084
NP_001311085
NP_001311086
NP_009061
NP_700359

n/a

Location (UCSC)Chr X: 47.45 – 47.48 Mbn/a
PubMed search[2]n/a
Wikidata
View/Edit Human

Zinc finger protein 41 is aprotein that in humans is encoded by theZNF41gene.[3][4]

This gene product is a likely zinc finger family transcription factor. It contains KRAB-A and KRAB-B domains that act as transcriptional repressors in related proteins, and multiple zinc finger DNA binding motifs and finger linking regions characteristic of theKruppel family. This gene is part of a gene cluster on chromosome Xp11.23. Several alternatively spliced transcript variants have been described, however, the full-length nature of only some of them is known.[4]

References

[edit]
  1. ^abcGRCh38: Ensembl release 89: ENSG00000147124Ensembl, May 2017
  2. ^"Human PubMed Reference:".National Center for Biotechnology Information, U.S. National Library of Medicine.
  3. ^Franze A, Archidiacono N, Rocchi M, Marino M, Grimaldi G (Jul 1991). "Isolation and expression analysis of a human zinc finger gene (ZNF41) located on the short arm of the X chromosome".Genomics.9 (4):728–36.doi:10.1016/0888-7543(91)90367-N.PMID 2037297.
  4. ^ab"Entrez Gene: ZNF41 zinc finger protein 41".

Further reading

[edit]

External links

[edit]

This article incorporates text from theUnited States National Library of Medicine, which is in thepublic domain.


(1) Basic domains
(1.1) Basicleucine zipper (bZIP)
(1.2) Basic helix-loop-helix (bHLH)
Group A
Group B
Group C
bHLH-PAS
Group D
Group E
Group F
bHLH-COE
(1.3)bHLH-ZIP
(1.4) NF-1
(1.5) RF-X
(1.6) Basic helix-span-helix (bHSH)
(2)Zinc finger DNA-binding domains
(2.1)Nuclear receptor(Cys4)
subfamily 1
subfamily 2
subfamily 3
subfamily 4
subfamily 5
subfamily 6
subfamily 0
(2.2) Other Cys4
(2.3) Cys2His2
(2.4) Cys6
(2.5) Alternating composition
(2.6) WRKY
(3.1)Homeodomain
Antennapedia
ANTP class
protoHOX
Hox-like
metaHOX
NK-like
other
(3.2) Paired box
(3.3)Fork head /winged helix
(3.4)Heat shock factors
(3.5) Tryptophan clusters
(3.6) TEA domain
  • transcriptional enhancer factor
(4)β-Scaffold factors with minor groove contacts
(4.1)Rel homology region
(4.2)STAT
(4.3) p53-like
(4.4)MADS box
(4.6)TATA-binding proteins
(4.7)High-mobility group
(4.9) Grainyhead
(4.10) Cold-shock domain
(4.11) Runt
(0) Other transcription factors
(0.2) HMGI(Y)
(0.3)Pocket domain
(0.5)AP-2/EREBP-related factors
(0.6) Miscellaneous


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