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| Parent institution | University of Oxford Wellcome Trust |
|---|---|
| Established | 1994; 31 years ago (1994) |
| Director | Holm Uhlig[1] |
| Staff | 470 |
| Key people | Yvonne Jones (deputy director) |
| Formerly called | Wellcome Trust Center for Human Genetics |
| Location | Henry Wellcome Building of Genomic Medicine,Oxford |
| Coordinates | 51°45′08″N1°12′55″W / 51.752248°N 1.215255°W /51.752248; -1.215255 |
 Interactive map of Centre for Human Genetics | |
| Website | www |
TheCentre for Human Genetics (CHG) is ahuman genetics research centre of the Nuffield Department of Medicine in theMedical Sciences Division, University of Oxford, funded by theWellcome Trust among others.[2]
The centre is located at theHenry Wellcome Building of Genomic Medicine, which cost £20 million and was officially opened in June 2000 withAnthony Monaco as the director.[3][4]
Within the CHG a number of 'cores' provide services to the researchers:
The Oxford Genomics Centre provides high throughput sequencing services, usingIllumina HiSeq4000 2500 and NextSeq500 and MiSeq.[5] They also offerOxford Nanopore MinION and PromethION sequencing.[5] There are also Array platforms for genotyping, gene expression, and methylation including Illuminia Infinium,Affymetrix andFluidigm.[6]
The Research Computing Core provides access to computer resources including 4120 cores and 4.2 PB of storage.[7]
The Transgenics Core provides access to genetically modified mice and cell lines.[8]
Cellular Imaging Core provides microscopy facilities including fluorescence microscopy (including Fluorescence Correlation Spectroscopy (FCS), Fluorescence Lifetime Correlation Spectroscopy (FLCS), Fluorescence Lifetime Imaging Microscopy (FLIM), Total Internal Reflection Fluorescence Microscopy (TIRF), Photoactivated Localisation Microscopy (PALM), Spectral Imaging (SI) and Single Particle Tracking (SPT).[9]
The CHG has been involved in many international statistical genetics advances including the Wellcome Trust Case Control Consortia (WTCCC, WTCCC2), the1000 Genomes Project and the InternationalHapMap Project.[10]
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