Function

Interactions

References

1. ^^abcGRCh38: Ensembl release 89: ENSG00000166483 –Ensembl, May 2017
2. ^^abcGRCm38: Ensembl release 89: ENSMUSG00000031016 –Ensembl, May 2017
3. ^"Human PubMed Reference:".National Center for Biotechnology Information, U.S. National Library of Medicine.
4. ^"Mouse PubMed Reference:".National Center for Biotechnology Information, U.S. National Library of Medicine.
5. ^Igarashi M, Nagata A, Jinno S, Suto K, Okayama H (September 1991). "Wee1(+)-like gene in human cells".Nature.353 (6339):80–3.Bibcode:1991Natur.353...80I.doi:10.1038/353080a0.PMID 1840647.S2CID 2920330.
6. ^"Entrez Gene: WEE1 WEE1 homolog (S. pombe)".
7. ^Wang, Y; Jacobs C; Hook K E; Duan H; Booher R N; Sun Y (April 2000). "Binding of 14-3-3beta to the carboxyl terminus of Wee1 increases Wee1 stability, kinase activity, and G2-M cell population".Cell Growth Differ.11 (4). UNITED STATES:211–9.ISSN 1044-9523.PMID 10775038.
8. ^Shen, M; Stukenberg P T; Kirschner M W; Lu K P (March 1998)."The essential mitotic peptidyl-prolyl isomerase Pin1 binds and regulates mitosis-specific phosphoproteins".Genes Dev.12 (5). UNITED STATES:706–20.doi:10.1101/gad.12.5.706.ISSN 0890-9369.PMC 316589.PMID 9499405.

Further reading

• Kino T, Pavlakis GN (2004)."Partner molecules of accessory protein Vpr of the human immunodeficiency virus type 1".DNA Cell Biol.23 (4):193–205.doi:10.1089/104454904773819789.PMID 15142377.
• Kino T, Chrousos GP (2004)."Human immunodeficiency virus type-1 accessory protein Vpr: a causative agent of the AIDS-related insulin resistance/lipodystrophy syndrome?".Ann. N. Y. Acad. Sci.1024 (1):153–67.Bibcode:2004NYASA1024..153K.doi:10.1196/annals.1321.013.PMID 15265780.S2CID 23655886.
• Le Rouzic E, Benichou S (2006)."The Vpr protein from HIV-1: distinct roles along the viral life cycle".Retrovirology.2 11.doi:10.1186/1742-4690-2-11.PMC 554975.PMID 15725353.
• Zhao RY, Elder RT (2005)."Viral infections and cell cycle G2/M regulation".Cell Res.15 (3):143–9.doi:10.1038/sj.cr.7290279.PMID 15780175.
• Zhao RY, Bukrinsky M, Elder RT (2005). "HIV-1 viral protein R (Vpr) & host cellular responses".Indian J. Med. Res.121 (4):270–86.PMID 15817944.
• Li L, Li HS, Pauza CD, et al. (2006)."Roles of HIV-1 auxiliary proteins in viral pathogenesis and host-pathogen interactions".Cell Res.15 (11–12):923–34.doi:10.1038/sj.cr.7290370.PMID 16354571.
• Igarashi M, Nagata A, Jinno S, et al. (1991). "Wee1(+)-like gene in human cells".Nature.353 (6339):80–3.Bibcode:1991Natur.353...80I.doi:10.1038/353080a0.PMID 1840647.S2CID 2920330.
• Baldin V, Ducommun B (1995). "Subcellular localisation of human wee1 kinase is regulated during the cell cycle".J. Cell Sci.108 (6):2425–32.doi:10.1242/jcs.108.6.2425.PMID 7673359.
• Watanabe N, Broome M, Hunter T (1995)."Regulation of the human WEE1Hu CDK tyrosine 15-kinase during the cell cycle".EMBO J.14 (9):1878–91.doi:10.1002/j.1460-2075.1995.tb07180.x.PMC 398287.PMID 7743995.
• McGowan CH, Russell P (1995)."Cell cycle regulation of human WEE1".EMBO J.14 (10):2166–75.doi:10.1002/j.1460-2075.1995.tb07210.x.PMC 398322.PMID 7774574.
• Kharbanda S, Yuan ZM, Taneja N, et al. (1994). "p56/p53lyn tyrosine kinase activation in mammalian cells treated with mitomycin C.".Oncogene.9 (10):3005–11.PMID 8084605.
• Heald R, McLoughlin M, McKeon F (1993). "Human wee1 maintains mitotic timing by protecting the nucleus from cytoplasmically activated Cdc2 kinase".Cell.74 (3):463–74.doi:10.1016/0092-8674(93)80048-J.PMID 8348613.S2CID 12091935.
• McGowan CH, Russell P (1993)."Human Wee1 kinase inhibits cell division by phosphorylating p34cdc2 exclusively on Tyr15".EMBO J.12 (1):75–85.doi:10.1002/j.1460-2075.1993.tb05633.x.PMC 413177.PMID 8428596.
• Taviaux SA, Demaille JG (1993). "Localization of human cell cycle regulatory genes CDC25C to 5q31 and WEE1 to 11p15.3-11p15.1 by fluorescence in situ hybridization".Genomics.15 (1):194–6.doi:10.1006/geno.1993.1032.PMID 8432534.
• Booher RN, Holman PS, Fattaey A (1997)."Human Myt1 is a cell cycle-regulated kinase that inhibits Cdc2 but not Cdk2 activity".J. Biol. Chem.272 (35):22300–6.doi:10.1074/jbc.272.35.22300.PMID 9268380.
• Zhou BB, Li H, Yuan J, Kirschner MW (1998)."Caspase-dependent activation of cyclin-dependent kinases during Fas-induced apoptosis in Jurkat cells".Proc. Natl. Acad. Sci. U.S.A.95 (12):6785–90.Bibcode:1998PNAS...95.6785Z.doi:10.1073/pnas.95.12.6785.PMC 22635.PMID 9618490.
• Taylor WR, DePrimo SE, Agarwal A, et al. (1999)."Mechanisms of G2 arrest in response to overexpression of p53".Mol. Biol. Cell.10 (11):3607–22.doi:10.1091/mbc.10.11.3607.PMC 25646.PMID 10564259.
• Wang Y, Jacobs C, Hook KE, et al. (2000). "Binding of 14-3-3beta to the carboxyl terminus of Wee1 increases Wee1 stability, kinase activity, and G2-M cell population".Cell Growth Differ.11 (4):211–9.PMID 10775038.
• Cichutek A, Brueckmann T, Seipel B, et al. (2001). "Comparative architectural aspects of regions of conserved synteny on human chromosome 11p15.3 and mouse chromosome 7 (including genes WEE1 and LMO1)".Cytogenet. Cell Genet.93 (3–4):277–83.doi:10.1159/000056998.PMID 11528126.S2CID 25807985.
• Elder RT, Yu M, Chen M, et al. (2001)."HIV-1 Vpr induces cell cycle G2 arrest in fission yeast (Schizosaccharomyces pombe) through a pathway involving regulatory and catalytic subunits of PP2A and acting on both Wee1 and Cdc25".Virology.287 (2):359–70.doi:10.1006/viro.2001.1007.PMID 11531413.

External links