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Uronolactonase

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Class of enzymes

uronolactonase

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The enzymeuronolactonase (EC 3.1.1.19)catalyzes the reaction

D-glucurono-6,2-lactone + H₂O

\rightleftharpoons

D-glucuronate

This enzyme belongs to the family ofhydrolases, specifically those acting on carboxylicester bonds. Thesystematic name isD-glucurono-6,2-lactone lactonohydrolase. It is also calledglucuronolactonase. It participates inascorbate and aldarate metabolism.

References

[edit]

Winkelman J, Lehninger AL (October 1958). "Aldono- and uronolactonases of animal tissues".The Journal of Biological Chemistry.233 (4):794–9.PMID 13587494.

Hydrolase:esterases (EC 3.1)

3.1.1:Carboxylic
ester hydrolases

Lipase

Phospholipase
- A1
- A2
- B

3.1.2:Thioesterase

3.1.3:Phosphatase

3.1.4:
Phosphodiesterase

3.1.6:Sulfatase

Nuclease (includes
deoxyribonuclease
andribonuclease)

3.1.11-16:
Exonuclease

Exodeoxyribonuclease	RecBCD
Exoribonuclease	Oligonucleotidase

3.1.21-31:
Endonuclease

Endodeoxyribonuclease	Deoxyribonuclease I Deoxyribonuclease II Deoxyribonuclease IV Restriction enzyme;see{{Restriction enzyme}} UvrABC endonuclease
Endoribonuclease	RNase III Drosha:Microprocessor complex Dicer:RNA-induced silencing complex RNase H 1 2A 2B 2C RNase P RNase A RNase Z RNase E 1 2 3 4/5 RNase T1
either deoxy- or ribo-	Nuclease S1 Mung bean nuclease Serratia marcescens nuclease Micrococcal nuclease

v t e Enzymes
Activity	Active site Binding site Catalytic triad Oxyanion hole Enzyme promiscuity Diffusion-limited enzyme Cofactor Enzyme catalysis
Regulation	Allosteric regulation Cooperativity Enzyme inhibitor Enzyme activator
Classification	EC number Enzyme superfamily Enzyme family List of enzymes
Kinetics	Enzyme kinetics Eadie–Hofstee diagram Hanes–Woolf plot Lineweaver–Burk plot Michaelis–Menten kinetics
Types	EC1Oxidoreductases (list) EC2Transferases (list) EC3Hydrolases (list) EC4Lyases (list) EC5Isomerases (list) EC6Ligases (list) EC7Translocases (list)

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