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Truncus arteriosus

From Wikipedia, the free encyclopedia
Structure during embryonic development
Truncus arteriosus
Heart of humanembryo of about twenty-four days. (Truncus arteriosus visible at top.)
Diagrams to illustrate the transformation of thebulbus cordis. Ao.Truncus arteriosus. Au.Atrium. B. Bulbus cordis. RV.Right ventricle. LV.Left ventricle. P.Pulmonary artery.
Details
PrecursorCardiogenic area
Gives rise toAorta,pulmonary artery
SystemCardiovascular system
Identifiers
MeSHD014338
TEarteriosus_by_E5.11.1.8.1.0.4 E5.11.1.8.1.0.4
FMA70301
Anatomical terminology

Thetruncus arteriosus is a structure that is present during embryonic development.[clarification needed] It is an arterial trunk that originates from both ventricles of the heart that later divides into theaorta and thepulmonary trunk.[1]

Structure

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See also:Heart development

The truncus arteriosus andbulbus cordis are divided by theaorticopulmonary septum. The truncus arteriosus gives rise to the ascendingaorta and thepulmonary trunk. The caudal end of the bulbus cordis gives rise to the smooth parts (outflow tract) of the left and right ventricles (aortic vestibule &conus arteriosus respectively).[2] The cranial end of the bulbus cordis (also known as the conus cordis) gives rise to the aorta and pulmonary trunk with the truncus arteriosus.

This makes its appearance in three portions.

  1. Two distal ridge-like thickenings project into the lumen of the tube: the truncal and bulbar ridges.[3] These increase in size, and ultimately meet and fuse to form a septum (aorticopulmonary septum), which takes a spiral course toward the proximal end of the truncus arteriosus. It divides the distal part of the truncus into two vessels, theaorta andpulmonary artery, which lie side by side above, but near the heart the pulmonary artery is in front of the aorta.
  2. Fourendocardial cushions appear in the proximal part of the truncus arteriosus in the region of the futuresemilunar valves; the manner in which these are related to the aortic septum is described below.
  3. Two endocardial thickenings—anterior and posterior—develop in the bulbus cordis and unite to form a short septum; this joins above with the aortic septum and below with the ventricular septum. The septum grows down into the ventricle as an oblique partition, which ultimately blends with the ventricular septum in such a way as to bring the bulbus cordis into communication with the pulmonary artery, and through the latter with the sixth pair ofaortic arches; while the left ventricle is brought into continuity with the aorta, which communicates with the remaining aortic arches.
  • Liver with the septum transversum. Human embryo 3 mm. long.
    Liver with the septum transversum. Human embryo 3 mm. long.
  • Illustration of truncus arteriosus in a fully formed heart
    Illustration of truncus arteriosus in a fully formed heart

Clinical significance

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Failure of the truncus arteriosus to close results in the condition known aspersistent truncus arteriosus, a rarecongenital heart defect. This is often just referred to astruncus arteriosus.Echocardiography is used to diagnose this condition.[4][5][6]Other pathologies of the truncus arteriosus includetransposition of the great vessels (arteries in this case), andtetralogy of Fallot.[7]

References

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Public domainThis article incorporates text in thepublic domain frompage 514 of the 20th edition ofGray's Anatomy(1918)

  1. ^Jaggers, James; Cole, Charles R. (2019)."55. Truncus Arteriosus". In Ungerleider, Ross M.; Nelson, Kristen; Cooper, David S.; Meliones, Jon N.; Jacobs, Jeffrey (eds.).Critical Heart Disease in Infants and Children (3rd ed.). Philadelphia: Elsevier. pp. 661–669.ISBN 978-1-4557-0760-7.
  2. ^Le, T., Bhushan, V., et al. 'First Aid for the USMLE STEP1'. 2009.
  3. ^Le, Tao; Bhushan, Vikas; Vasan, Neil (2010).First Aid for the USMLE Step 1: 2010 20th Anniversary Edition. USA:The McGraw-Hill Companies, Inc. pp. 123.ISBN 978-0-07-163340-6.
  4. ^"Truncus Arteriosus | Pediatric Echocardiography".
  5. ^"Truncus Arteriosus Imaging: Overview, Radiography, Computed Tomography". 16 October 2021.
  6. ^"Truncus arteriosus - Diagnosis and treatment - Mayo Clinic".Mayo Clinic.
  7. ^Le, Tao; Bhushan, Vikas; Vasan, Neil (2010).First Aid for the USMLE Step 1: 2010 20th Anniversary Edition. USA:The McGraw-Hill Companies, Inc. pp. 123.ISBN 978-0-07-163340-6.

External links

[edit]
Development of thecirculatory system
Heart
Tubular heart
Chamber formation
Other
Vessels
Arteries
Veins
Lymph vessels
Other
Extraembryonic
hemangiogenesis
Fetal circulation
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