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| Clinical data | |
|---|---|
| Trade names | Viru-Merz |
| AHFS/Drugs.com | International Drug Names |
| Routes of administration | Topical (gel) |
| ATC code | |
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| Identifiers | |
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| CAS Number | |
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| UNII | |
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| NIAID ChemDB | |
| CompTox Dashboard(EPA) | |
| ECHA InfoCard | 100.053.409 |
| Chemical and physical data | |
| Formula | C16H28N2O2 |
| Molar mass | 280.412 g·mol−1 |
| 3D model (JSmol) | |
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Tromantadine is anantiviral medicine used to treatherpes simplex virus. It is available in atopical gel under trade namesViru-Merz andViru-Merz Serol. Its performance is similar toaciclovir.[1][2]
Likerimantadine,amantadine, andadapromine, tromantadine is a derivative ofadamantane.
Tromantadine inhibits the early and late events in thevirus replication cycle.[3] It changes theglycoproteins of the host cells, therefore impeding the absorption of the virus. It inhibits penetration of the virus. It also preventsuncoating of thevirions.[citation needed]
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