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Triclofos

From Wikipedia, the free encyclopedia
Pharmaceutical drug
Pharmaceutical compound
Triclofos
Clinical data
Trade namesTriclos, others
AHFS/Drugs.comInternational Drug Names
ATC code
Legal status
Legal status
Identifiers
  • 2,2,2-trichloroethanol dihydrogen phosphate
CAS Number
PubChemCID
ChemSpider
UNII
KEGG
ChEMBL
CompTox Dashboard(EPA)
ECHA InfoCard100.005.624Edit this at Wikidata
Chemical and physical data
FormulaC2H4Cl3O4P
Molar mass229.37 g·mol−1
3D model (JSmol)
  • ClC(Cl)(Cl)COP(=O)(O)O
  • InChI=1S/C2H4Cl3O4P/c3-2(4,5)1-9-10(6,7)8/h1H2,(H2,6,7,8) checkY
  • Key:YYQRGCZGSFRBAM-UHFFFAOYSA-N checkY
 ☒NcheckY (what is this?)  (verify)

Triclofos (brand namesTriclos,Pedicloryl) is asedative drug used rarely for treatinginsomnia.[2]

Triclofos is aprodrug which is metabolised in the liver into the active drugtrichloroethanol. The half-life of triclofos is fairly long and it may cause drowsiness the next day. Trichloroethanol may cause liver damage and triclofos should not be used for extended periods.

Triclofos is no longer available in the United States.[3]

Side effects

[edit]

Side effects may include:

References

[edit]
  1. ^Anvisa (2023-03-31)."RDC Nº 784 - Listas de Substâncias Entorpecentes, Psicotrópicas, Precursoras e Outras sob Controle Especial" [Collegiate Board Resolution No. 784 - Lists of Narcotic, Psychotropic, Precursor, and Other Substances under Special Control] (in Brazilian Portuguese).Diário Oficial da União (published 2023-04-04).Archived from the original on 2023-08-03. Retrieved2023-08-16.
  2. ^Erhorn S (2007)."Triclofos".xPharm: The Comprehensive Pharmacology Reference. Elsevier. pp. 1–4.doi:10.1016/B978-008055232-3.62797-7.ISBN 978-0-08-055232-3. Retrieved29 February 2020.
  3. ^"Drugs@FDA: FDA-Approved Drugs".www.accessdata.fda.gov. Archived fromthe original on May 1, 2017. Retrieved29 February 2020.


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