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| Other names | N-[3-[4-(2-Diethylaminoethoxy)phenyl]-1-(dipropylamino)-1-oxopropan-2-yl]benzamide |
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| Chemical and physical data | |
| Formula | C28H41N3O3 |
| Molar mass | 467.654 g·mol−1 |
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Tiropramide is theInternational nonproprietary name of anantispasmodic drug.[1]
Theacylation ofracemictyrosine (1) withbenzoyl chloride gives N,O-dibenzoyl-tyrosine (2).Amide formation withdipropylamine (3) using themixed anhydride method gives the intermediate (4).Hydrolysis of thephenolic ester withsodium hydroxide forms (5), which isalkylated withClCH2CH2N(CH2CH3)2 to produce theether tiropramide.[2][3]
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