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Teprenone

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Chemical compound

Pharmaceutical compound

Teprenone
Clinical data

Trade names	Selbex
AHFS/Drugs.com	International Drug Names
ATC code	A02BX15 (WHO) QA02BX15 (WHO)
Legal status
Legal status	In general: ℞ (Prescription only)
Identifiers
IUPAC name (5E,9E,13E)-6,10,14,18-tetramethylnonadeca-5,9,13,17-tetraen-2-one
CAS Number	6809-52-5
PubChemCID	5282199
DrugBank	DB15955^Y
ChemSpider	29787024
UNII	S8S8451A4O
KEGG	D01827^Y
ChEBI	CHEBI:31649
ChEMBL	ChEMBL79686
CompTox Dashboard(EPA)	DTXSID901166719
Chemical and physical data
Formula	C₂₃H₃₈O
Molar mass	330.556 g·mol⁻¹
3D model (JSmol)	Interactive image
SMILES CC(C)=CCC\C(C)=C\CC\C(C)=C\CC\C(C)=C\CCC(C)=O
InChI InChI=1S/C23H38O/c1-19(2)11-7-12-20(3)13-8-14-21(4)15-9-16-22(5)17-10-18-23(6)24/h11,13,15,17H,7-10,12,14,16,18H2,1-6H3/b20-13+,21-15+,22-17+ Key:HUCXKZBETONXFO-NJFMWZAGSA-N
(verify)

Teprenone (orgeranylgeranylacetone), sold under the brand nameSelbex,^[1] is amedication used for the treatment ofgastric ulcers.^[2]

^Liu X, Jia B, Lin S (January 1996). "[Teprenone in the treatment of chronic superficial gastritis, a multicentre study]".Zhonghua Nei Ke Za Zhi (in Chinese).35 (1):12–4.PMID 9275638.
^Kitahata H, Nozaki J, Kawahito S, Tomino T, Oshita S (September 2008)."Low-dose sevoflurane inhalation enhances late cardioprotection from the anti-ulcer drug geranylgeranylacetone".Anesth. Analg.107 (3):755–61.doi:10.1213/ane.0b013e31817f0e61.PMID 18713879.S2CID 19387865.

v t e Drugs forpeptic ulcer andGERD/GORD (A02B)
H₂ antagonists ("-tidine")	Cimetidine Famotidine Lafutidine Lavoltidine (loxtidine) Niperotidine Nizatidine Ranitidine^#‡ Roxatidine
Prostaglandins (E)/ analogues ("-prost-")	Misoprostol Enprostil
Proton-pump inhibitors ("-prazole")	Anaprazole Azeloprazole Dexlansoprazole Dexrabeprazole Esomeprazole Ilaprazole Lansoprazole Omeprazole^# Pantoprazole Picoprazole Rabeprazole Tenatoprazole Timoprazole
Potassium-competitive acid blockers ("-prazan")	Fexuprazan Linaprazan Revaprazan Soraprazan Tegoprazan Vonoprazan Zastaprazan
Others	Aceglutamide aluminum Acetoxolone Alginic acid Arbaclofen placarbil Bismuth subcitrate Carbenoxolone Cetraxate Gefarnate Irsogladine Lesogaberan Pirenzepine Proglumide Rebamipide Sucralfate Sulglicotide Telenzepine Teprenone Troxipide Zinc L-carnosine Zolimidine
Combinations	Bismuth subcitrate/metronidazole/tetracycline Omeprazole/amoxicillin/rifabutin Vonoprazan/amoxicillin Vonoprazan/amoxicillin/clarithromycin
See also:Helicobacter pylori* eradication protocols*
^#WHO-EM ^‡Withdrawn from market Clinical trials: ^†Phase III ^§Never to phase III

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