This gene belongs to a family of genes that function asreceptors fortachykinins. Receptor affinities are specified by variations in the 5'-end of the sequence. The receptors belonging to this family are characterized by interactions with G proteins and 7 hydrophobic transmembrane regions. This gene encodes the receptor for the tachykinin neurokinin 3, also referred to asneurokinin B.[6]
^"Human PubMed Reference:".National Center for Biotechnology Information, U.S. National Library of Medicine.
^"Mouse PubMed Reference:".National Center for Biotechnology Information, U.S. National Library of Medicine.
^Huang RR, Cheung AH, Mazina KE, Strader CD, Fong TM (Apr 1992). "cDNA sequence and heterologous expression of the human neurokinin-3 receptor".Biochemical and Biophysical Research Communications.184 (2):966–72.doi:10.1016/0006-291X(92)90685-E.PMID1374246.
^Quartara L, Altamura M (Aug 2006). "Tachykinin receptors antagonists: from research to clinic".Current Drug Targets.7 (8):975–92.doi:10.2174/138945006778019381.PMID16918326.
Takahashi K, Tanaka A, Hara M, Nakanishi S (Mar 1992). "The primary structure and gene organization of human substance P and neuromedin K receptors".European Journal of Biochemistry.204 (3):1025–33.doi:10.1111/j.1432-1033.1992.tb16724.x.PMID1312928.
Huang RR, Cheung AH, Mazina KE, Strader CD, Fong TM (Apr 1992). "cDNA sequence and heterologous expression of the human neurokinin-3 receptor".Biochemical and Biophysical Research Communications.184 (2):966–72.doi:10.1016/0006-291X(92)90685-E.PMID1374246.
Dion S, Corcos J, Carmel M, Drapeau G, Regoli D (1988). "Substance P and neurokinins as stimulants of the human isolated urinary bladder".Neuropeptides.11 (2):83–7.doi:10.1016/0143-4179(88)90015-7.PMID2452993.S2CID13728584.
Brunelleschi S, Bordin G, Colangelo D, Viano I (Jun 1998). "Tachykinin receptors on human monocytes: their involvement in rheumatoid arthritis".Neuropeptides.32 (3):215–23.doi:10.1016/S0143-4179(98)90040-3.PMID10189055.S2CID40222022.
Page NM, Woods RJ, Gardiner SM, Lomthaisong K, Gladwell RT, Butlin DJ, Manyonda IT, Lowry PJ (Jun 2000). "Excessive placental secretion of neurokinin B during the third trimester causes pre-eclampsia".Nature.405 (6788):797–800.Bibcode:2000Natur.405..797P.doi:10.1038/35015579.PMID10866201.S2CID4392048.
Page NM, Dakour J, Morrish DW (Jul 2006). "Gene regulation of neurokinin B and its receptor NK3 in late pregnancy and pre-eclampsia".Molecular Human Reproduction.12 (7):427–33.doi:10.1093/molehr/gal025.PMID16709596.
"Tachykinin Receptors: NK3".IUPHAR Database of Receptors and Ion Channels. International Union of Basic and Clinical Pharmacology. Archived fromthe original on 2012-05-31. Retrieved2008-12-09.