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TRPC4AP

From Wikipedia, the free encyclopedia
Protein-coding gene in the species Homo sapiens
TRPC4AP
Identifiers
AliasesTRPC4AP, C20orf188, PPP1R158, TRRP4AP, TRUSS, transient receptor potential cation channel subfamily C member 4 associated protein
External IDsOMIM:608430;MGI:1930751;HomoloGene:9224;GeneCards:TRPC4AP;OMA:TRPC4AP - orthologs
Gene location (Human)
Chromosome 20 (human)
Chr.Chromosome 20 (human)[1]
Chromosome 20 (human)
Genomic location for TRPC4AP
Genomic location for TRPC4AP
Band20q11.22Start35,002,404bp[1]
End35,092,807bp[1]
Gene location (Mouse)
Chromosome 2 (mouse)
Chr.Chromosome 2 (mouse)[2]
Chromosome 2 (mouse)
Genomic location for TRPC4AP
Genomic location for TRPC4AP
Band2 H1|2 77.26 cMStart155,476,191bp[2]
End155,534,304bp[2]
RNA expression pattern
Bgee
HumanMouse (ortholog)
Top expressed in
  • granulocyte

  • right adrenal cortex

  • anterior pituitary

  • gastric mucosa

  • body of pancreas

  • left adrenal gland

  • stromal cell of endometrium

  • left adrenal cortex

  • gastrocnemius muscle

  • upper lobe of left lung
Top expressed in
  • spermatocyte

  • muscle of thigh

  • entorhinal cortex

  • thymus

  • perirhinal cortex

  • CA3 field

  • granulocyte

  • cerebellar cortex

  • superior frontal gyrus

  • dentate gyrus of hippocampal formation granule cell
More reference expression data
BioGPS
More reference expression data
Gene ontology
Molecular function
Cellular component
Biological process
Sources:Amigo /QuickGO
Orthologs
SpeciesHumanMouse
Entrez

26133

56407

Ensembl

ENSG00000100991

ENSMUSG00000038324

UniProt

Q8TEL6

Q9JLV2

RefSeq (mRNA)

NM_015638
NM_199368

NM_001163452
NM_019828

RefSeq (protein)

NP_056453
NP_955400

NP_001156924
NP_062802

Location (UCSC)Chr 20: 35 – 35.09 MbChr 2: 155.48 – 155.53 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Trpc4-associated protein is aprotein that in humans is encoded by theTRPC4APgene.

Interactions

[edit]

TRPC4AP has been shown tointeract withTNFRSF1A.[5][clarification needed]

See also

[edit]

References

[edit]
  1. ^abcGRCh38: Ensembl release 89: ENSG00000100991Ensembl, May 2017
  2. ^abcGRCm38: Ensembl release 89: ENSMUSG00000038324Ensembl, May 2017
  3. ^"Human PubMed Reference:".National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^"Mouse PubMed Reference:".National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^Soond SM, Terry JL, Colbert JD, Riches DW (Nov 2003)."TRUSS, a novel tumor necrosis factor receptor 1 scaffolding protein that mediates activation of the transcription factor NF-kappaB".Mol. Cell. Biol.23 (22):8334–44.doi:10.1128/MCB.23.22.8334-8344.2003.PMC 262424.PMID 14585990.
Ligand-gated
Voltage-gated
Constitutively active
Proton-gated
Voltage-gated
Calcium-activated
Inward-rectifier
Tandem pore domain
Voltage-gated
Miscellaneous
Cl:Chloride channel
H+:Proton channel
M+:CNG cation channel
M+:TRP cation channel
H2O (+solutes):Porin
Cytoplasm:Gap junction
By gating mechanism
Ion channel class
see alsodisorders
TRPA
Activators
Blockers
TRPC
Activators
Blockers
TRPM
Activators
Blockers
TRPML
Activators
Blockers
TRPP
Activators
Blockers
TRPV
Activators
Blockers


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