Movatterモバイル変換


[0]ホーム

URL:


Jump to content
WikipediaThe Free Encyclopedia
Search

Sulfonmethane

From Wikipedia, the free encyclopedia
Chemical compound
Pharmaceutical compound
Sulfonmethane
Clinical data
ATC code
  • none
Legal status
Legal status
Identifiers
  • 2,2-bis(ethylsulfonyl)propane
CAS Number
PubChemCID
ChemSpider
UNII
CompTox Dashboard(EPA)
ECHA InfoCard100.003.704Edit this at Wikidata
Chemical and physical data
FormulaC7H16O4S2
Molar mass228.32 g·mol−1
3D model (JSmol)
  • O=S(=O)(C(C)(C)S(=O)(=O)CC)CC
  • InChI=1S/C7H16O4S2/c1-5-12(8,9)7(3,4)13(10,11)6-2/h5-6H2,1-4H3 checkY
  • Key:CESKLHVYGRFMFP-UHFFFAOYSA-N checkY
 ☒NcheckY (what is this?)  (verify)

Sulfonmethane (sulfonomethane,sulfonal,acetone diethyl sulfone)[1] is a chemical compound first synthesized by Eugen Baumann in 1888 and introduced as ahypnotic drug by Alfred Kast later on, but now superseded by newer and safer sedatives.[2] Its appearance is either in colorless crystalline or powdered form. In United States, it is scheduled as aSchedule III drug in theControlled Substances Act.[3]

Chemistry

[edit]

Sulfonal is prepared by condensingacetone withethyl mercaptan in the presence ofhydrochloric acid, the mercaptol (CH3)2C(SC2H5)2 formed being subsequentlyoxidized bypotassium permanganate. It is also formed by the action ofalcoholicpotash andmethyl iodide on ethylidene diethyl sulfine, CH3CH(SO2C2H5)2 (which is formed by the oxidation of dithioacetal withpotassium permanganate). Itcrystallizes inprisms melting at 125 C, which are practically insoluble in cold water, but dissolves in 15 parts of hot water and also inalcohol andether.

See also

[edit]

References

[edit]
  1. ^DE Patent 46333
  2. ^American Heritage Dictionary
  3. ^"DEA Scheduling".

Further reading

[edit]
  • Kast A (1888).Sulfonal, ein neues Schlafmittel (in German). Berlin.{{cite book}}: CS1 maint: location missing publisher (link)
  • Wendt EC (1888)."Sulfonal, a new Hypnotic".The Medical Record.33 (22). New York:597–598.
  • Bayer (1889)."Sulfonal".The Cincinnati Lancet-Clinic.22. Cincinnati: J. C. Culbertson: 2.
GABAA
Alcohols
Barbiturates
Benzodiazepines
Carbamates
Imidazoles
Monoureides
Neurosteroids
Nonbenzodiazepines
Phenols
Piperidinediones
Quinazolinones
Others
GABAB
H1
Antihistamines
Antidepressants
Antipsychotics
α2-Adrenergic
5-HT2A
Antidepressants
Antipsychotics
Others
Melatonin
Orexin
α2δVDCC
Others
Inhalational
Injection
Phenols
Barbiturates
Benzodiazepines
Opioids
Arylcyclohexylamines
Neuroactive steroids
Others
Alcohols
Barbiturates
Benzodiazepines
Carbamates
Flavonoids
Imidazoles
Kava constituents
Monoureides
Neuroactive steroids
Nonbenzodiazepines
Phenols
Piperidinediones
Pyrazolopyridines
Quinazolinones
Volatiles/gases
Others/unsorted
Retrieved from "https://en.wikipedia.org/w/index.php?title=Sulfonmethane&oldid=1284962526"
Categories:
Hidden categories:

[8]ページ先頭

©2009-2025 Movatter.jp