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Sulbentine

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Chemical compound

Pharmaceutical compound

Sulbentine
Clinical data

ATC code	D01AE09 (WHO)
Identifiers
IUPAC name 3,5-bis(phenylmethyl)-1,3,5-thiadiazinane-2-thione
CAS Number	350-12-9^Y
PubChemCID	67686
ChemSpider	61005^N
UNII	D0NR12WK9J
KEGG	D01335^Y
CompTox Dashboard(EPA)	DTXSID7046257
ECHA InfoCard	100.005.907
Chemical and physical data
Formula	C₁₇H₁₈N₂S₂
Molar mass	314.46 g·mol⁻¹
3D model (JSmol)	Interactive image
SMILES c1ccc(cc1)CN2CN(C(=S)SC2)Cc3ccccc3
InChI InChI=1S/C17H18N2S2/c20-17-19(12-16-9-5-2-6-10-16)13-18(14-21-17)11-15-7-3-1-4-8-15/h1-10H,11-14H2^N Key:QFVAWNPSRQWSDU-UHFFFAOYSA-N^N
^NY (what is this?) (verify)

Sulbentine (ordibenzthione) is anantifungal.^[1]

^Hänel H, Raether W, Dittmar W (1988). "Evaluation of fungicidal action in vitro and in a skin model considering the influence of penetration kinetics of various standard antimycotics".Annals of the New York Academy of Sciences.544 (1):329–37.Bibcode:1988NYASA.544..329H.doi:10.1111/j.1749-6632.1988.tb40417.x.PMID 3214073.S2CID 13183316.

Wall/
membrane

Ergosterol
inhibitors

Imidazoles	Topical:bifonazole^‡ butoconazole chlormidazole^‡ climbazole clotrimazole^# croconazole^‡ eberconazole econazole fenticonazole^‡ flutrimazole isoconazole ketoconazole luliconazole miconazole^# neticonazole^‡ omoconazole^‡ oxiconazole sertaconazole sulconazole tioconazole Systemic: ketoconazole
Triazoles	Topical:efinaconazole fluconazole^# terconazole Systemic:fluconazole^# fosfluconazole fosravuconazole hexaconazole^‡ isavuconazole itraconazole^# oteseconazole posaconazole voriconazole^# Unknown:albaconazole^‡ ravuconazole^†
Thiazoles	Topical:abafungin^‡

Allylamines	Topical:naftifine terbinafine Systemic: terbinafine
Benzylamines	Topical:butenafine

Others

Intracellular

Pyrimidine analogues/ thymidylate synthase inhibitors	Systemic:flucytosine^#
Mitotic inhibitors	Systemic:griseofulvin^#
Aminoacyl tRNA synthetase inhibitors	Topical:tavaborole

Others

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