St Mary's Hospital
Imperial College Healthcare NHS Trust
The Clarence Memorial Wing at St Mary's Hospital
Shown in Westminster
Geography
Location	Paddington,London, England, United Kingdom
Coordinates	51°31′2″N0°10′23″W / 51.51722°N 0.17306°W /51.51722; -0.17306
Organisation
Care system	National Health Service
Type	Teaching
Affiliated university	Imperial College London
Services
Emergency department	Major Trauma Centre – (adult and children)
Beds	484[1]
History
Founded	1845; 181 years ago (1845)
Links
Website	www.imperial.nhs.uk/our-locations/st-marys-hospital
Lists	Hospitals in England

St Mary's Hospital is ateaching hospital inPaddington, in theCity of Westminster, London, founded in 1845. Since the UK's firstacademic health science centre was created in 2008, it has been operated byImperial College Healthcare NHS Trust, which also operatesCharing Cross Hospital,Hammersmith Hospital,Queen Charlotte's and Chelsea Hospital and theWestern Eye Hospital.^[2]

Until 1988 the hospital ranSt Mary's Hospital Medical School, part of the federalUniversity of London. In 1988 it merged withImperial College London, and then withCharing Cross and Westminster Medical School in 1997 to formImperial College School of Medicine. In 2007 Imperial College became an independent institution when it withdrew from theUniversity of London.^[3]

The original block of St Mary's Hospital in Norfolk Place was designed byThomas Hopper in theclassical style.^[4] It first opened its doors to patients in 1851, the last of the greatvoluntary hospitals to be founded.^[5] Among St Mary's founders was the surgeonIsaac Baker Brown, a controversial figure who performed numerousclitoridectomies at the London Surgical Home, his hospital for women, and who "immediately set to work to remove theclitoris whenever he had the opportunity of doing so."^[6] It was at St Mary's Hospital thatC.R. Alder Wright first synthesizeddiamorphine in 1874.^[7]

The Clarence Memorial Wing, designed bySir William Emerson and built with its main frontage on Praed Street, opened in 1904.^[8] It was at the hospital thatAlexander Fleming discoveredpenicillin in 1928.^[9] Fleming's laboratory has been restored and incorporated into a museum about the discovery and his life and work.^{[9][note 1]}

The private Lindo wing, where there have been several royal and celebrity births, opened in November 1937;^[11] it was financed by businessman and hospital board member Frank Charles Lindo, who made a large donation before his death in 1938.^[12]

Following the 1944 publication of a report by SirWilliam Goodenough advocating a minimum size for teaching hospitals,^[13] and following the formation of theNational Health Service in the 1948, several local hospitals became affiliated to St Mary's Hospital. These includedPaddington General Hospital,^[14] theSamaritan Hospital for Women^[15] and theWestern Eye Hospital.^[16]

In the 1950s, Felix Eastcott, a consultant surgeon and deputy director of the surgical unit at St Mary's Hospital, carried out pioneering work oncarotid endarterectomy designed to reduce the risk ofstroke.^[17] Paddington General Hospital closed and relocated services to the Paddington basin site in November 1986^[14] and, in common with the other London teaching hospitals who lost their independence at that time, the medical school of St Mary's Hospital merged with that ofImperial College London in 1988.^[5]

In 1987, as part of on-going rationalisation within the NHS, the hundred-year-oldPaddington Green Children's Hospital was closed down, thelisted buildings sold off and its services absorbed into St Mary's.^[18]

Royal family

• Alexander Windsor, Earl of Ulster (born 1974) – son of theDuke andDuchess of Gloucester^[19]
• Lady Davina Windsor (born 1977) – daughter of the Duke and Duchess of Gloucester^[20]
• Peter Phillips (born 1977) – son ofthe Princess Royal andMark Phillips^[21]
• Lord Frederick Windsor (born 1979) – son ofPrince andPrincess Michael of Kent^[22]
• Lady Rose Gilman (born 1980) – daughter ofDuke andDuchess of Gloucester^[23]
• Zara Tindall (born 1981) – daughter of the Princess Royal and Mark Phillips^[24]
• Lady Gabriella Kingston (born 1981) – daughter of Prince and Princess Michael of Kent^[25]
• William, Prince of Wales (born 1982) – first son ofKing Charles III andDiana, Princess of Wales^[26]
• Princess Theodora of Greece and Denmark (born 1983) – daughter of theKing Constantine II of Greece andQueen Anne-Marie of Greece^[27]
• Prince Harry, Duke of Sussex (born 1984) – second son of King Charles III and Diana, Princess of Wales^[28]
• Prince Philippos of Greece and Denmark (born 1986)  – son ofKing Constantine II of Greece andQueen Anne-Marie of Greece^[29]
• Edward Windsor, Lord Downpatrick (born 1988) – son ofGeorge Windsor, Earl of St Andrews andSylvana Windsor, Countess of St Andrews^[30]
• Prince George of Wales (born 2013) – first son of William, Prince of Wales, andCatherine, Princess of Wales^[31]
• Princess Charlotte of Wales (born 2015) – daughter of William, Prince of Wales, and Catherine, Princess of Wales^[32]
• Prince Louis of Wales (born 2018) – second son of William, Prince of Wales, and Catherine, Princess of Wales^[33]

Other notable births

• Seal (born 1963)  – British musician^[34]
• Olivia Robertson (1917–2013) – author, co-founder and High Priestess of theFellowship of Isis^[35]
• Elvis Costello (born 1954) – British musician^[36]
• Kiefer Sutherland (born 1966) – Canadian actor^[37]
• Lady Charlotte Wellesley (born 1990) – daughter of the 9th Duke of Wellington^[38]
• Michael Page (born 1987) – British professional boxer and mixed martial artist^[39]
• Louis Spencer, Viscount Althorp (born 1994) – heir apparent to theSpencer earldom, nephew of Diana, Princess of Wales and first cousin of the Prince of Wales and the Duke of Sussex^[40]
• Admiral Schofield (born 1997) – American basketball player, currently with theOrlando Magic^[41]

• Arthur Cecil Alport – physician who first identifiedAlport syndrome in 1927^[42]
• Roger Bannister – first man to run afour-minute mile, professor of neurology^[43]
• Dorothy Bannon – matron 1922–1928, subsequently first Chief Matron-in-Charge of theLondon County Council Hospital and School Nursing Service^[44]
• Aleck Bourne – gynaecologist best known for his 1938 trial, a landmark case in abortion law^[45]
• William Broadbent – 19th-century neurologist and cardiologist^[46]
• John Scott Burdon-Sanderson – Regius Professor ofMedicine at theUniversity of Oxford andRoyal Medal winner^[47]
• J. Jackson Clarke  – pathologist, surgeon, and cancer researcher^[48]
• Leonard Colebrook – physician and bacteriologist,MBBS in 1906, who, in 1935, showedProntosil was effective againsthaemolyticstreptococcus ofpuerperal fever^[49]
• Zachary Cope – surgeon and medical historian^[50]
• Ara Darzi, Baron Darzi of Denham – Health Minister^[51]
• Alexander Fleming – awarded theNobel Prize for discovery ofpenicillin^[52]
• Nim Hall – England rugby captain^[53]
• John Henry – clinicaltoxicologist who did crucial work onpoisoning anddrug overdose^[54]
• Amanda Herbert – cytopathologist andhistopathologist, editor ofCytopathology from 2008 to 2014 and co-editor ofEurocytology.eu^[55]
• Albert Neuberger – professor of chemicalpathology^[56][57]
• Tom Oppé – professor of paediatrics^[58]
• Tuppy Owen-Smith – international rugby player and cricketer^[59][60]
• William Stanley Peart – professor of medicine, isolated and determined the structure ofangiotensin^[61]
• Arthur Porritt, Baron Porritt – President of theBritish Medical Association and theRoyal College of Surgeons of England andGovernor-General of New Zealand^[62]
• Rodney Robert Porter – awarded theNobel Prize for research on the chemical structure ofantibodies^[63]
• Bernard Spilsbury – pathologist and one of the pioneers of modernforensic medicine^[64]
• Joseph Toynbee – otologist^[65]
• Augustus Waller – whose research led to the invention of theelectrocardiogram (ECG)^[66]
• J. P. R. Williams – international rugby player^[67]
• Almroth Wright – advancedvaccination through the use ofautogenous vaccines^[68]
• Charles Romley Alder Wright – first person to synthesize heroin in 1874^[69]
• Wu Lien-teh – later to be the Plague fighter of China^[70]

St Mary's Hospital is located besideLondon Paddington railway station, the principal station of theGreat Western Railway and its successors. In celebration of the association, aBritish Rail Class 43 (InterCity 125) locomotive, 43142, was namedSt Mary's Hospital, Paddington on 4 November 1986. The locomotive is still in service but, following changes of ownership, the name has now been removed. One of the large metal nameplates was acquired by the hospital, and is now displayed in the foyer of the Cambridge Wing.^[71]

St Mary's Hospital is one of fourmajor trauma centres inLondon. The other three areKing's College Hospital inDenmark Hill,The Royal London Hospital inWhitechapel, andSt George's Hospital inTooting.^[72]

The charity Cosmic is an independent charity, supporting the work of the neonatal and paediatric intensive care services at St Mary's Hospital, Paddington and Queen Charlotte's Hospital, Hammersmith, both part of Imperial College Healthcare NHS Trust, London. The charity funds a range of specialist equipment for the units, including ventilators and patient monitoring systems for those being treated on the wards,^[73] as well as providing practical and emotional support to families.^[74]

In the Britishpreschoolanimated television seriesPeppa Pig, Peppa's little sisterEvie was born at the Lindo Wing on 20 May 2025.^[75]

• List of hospitals in England

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• Christian hospitals
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• Hospitals established in 1845
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