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Sohini Ramachandran

From Wikipedia, the free encyclopedia
Computational biology professor
Sohini Ramachandran
EducationStanford University
Alma materStanford University
Scientific career
ThesisThe signature of historical migrations on human population genetic data (2007)
Doctoral advisorMarcus Feldman
Websitehttps://brown.edu/Research/Ramachandran_Lab/

Sohini Ramachandran is professor atBrown University known for her work inevolutionary biology andpopulation genetics.

Early life and education

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Ramachandran's parents were both professors.[1] In the summer before her senior year of high school, Ramachandran completed a research project in plant genomics under the guidance ofMarcus Feldman, which won her the fourth place prize in the 1998 Westinghouse Science Talent Search,[2] where when she was the youngest finalist in the group.[3] Ramachandran earned a B.S. fromStanford University in 2002. She went on to complete a Ph.D. atStanford University in the Department of Biological Sciences, advised byMarcus Feldman. Her dissertation research was dissertation was titled "The signature of historical migrations on human population genetic data."[4] Following her PhD, she was in theHarvard Society of Fellows as a postdoctoral researcher with John Wakeley inHarvard University's Department of Organismic and Evolutionary Biology.[5] She moved to Brown University in 2010 and was promoted to professor in 2021.[5] In 2019, she was a fellow at theSwedish Collegium for Advanced Study.[6]

Research

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Ramachandran's research group uses statistical and mathematical modeling techniques to studyevolutionary biology andpopulation genetics. Her early research examined the genetic relationships originating within people from Africa,[7][8] where she showed that diversity decreases as distance from Africa increases.[9] She has also investigated the use of genetic tools to track infectious diseases[10][11] and shown that while more outbreaks are occurring, fewer people are getting infected.[12] She has also shown a lack of genetic evidence for selection for language at theFOXP2 site.[13]

Selected publications

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Honors and awards

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In 2012, Ramachandran received aSloan Research Fellowship[14] and was named a Pew Scholar.[15] From Brown University she has received the Henry Merritt Wriston Fellowship (2016)[16] and the Philip J. Bray Award for excellence in teaching.[17] In 2019, she received aPresidential Early Career Award in Science and Engineering.[18][19]

References

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  1. ^Chen, Ling-Ling; Claw, Katrina G.; Ramachandran, Sohini (2016)."A two-fold challenge: the experience of women of color in genomics".Genome Biology.17 (1): 210.doi:10.1186/s13059-016-1075-0.ISSN 1474-760X.PMC 5059990.PMID 27729075.
  2. ^Chiu, Yvonne (1998-03-09)."Fair Oaks teen gets national honor".The Sacramento Bee. p. 2. Retrieved2022-04-17.
  3. ^Alcala, Carlos (1998-01-28)."Fair Oaks teen, like sister, is on academic fast track".The Sacramento Bee. pp. [1],[2]. Retrieved2022-04-17.
  4. ^Ramachandran, Sohini (2007).The signature of historical migrations on human population genetic data (Thesis).OCLC 269371999.
  5. ^ab"Sohini Ramachandran Lab: people".brown.edu. Retrieved2022-04-17.
  6. ^"SCAS: Sohini Ramachandran".www.swedishcollegium.se. Retrieved2022-01-22.
  7. ^Ramachandran, Sohini; Deshpande, Omkar; Roseman, Charles C.; Rosenberg, Noah A.; Feldman, Marcus W.; Cavalli-Sforza, L. Luca (2005)."Support from the relationship of genetic and geographic distance in human populations for a serial founder effect originating in Africa".Proceedings of the National Academy of Sciences.102 (44):15942–15947.Bibcode:2005PNAS..10215942R.doi:10.1073/pnas.0507611102.ISSN 0027-8424.PMC 1276087.PMID 16243969.
  8. ^Henn, Brenna M.; Gignoux, Christopher R.; Jobin, Matthew; Granka, Julie M.; Macpherson, J. M.; Kidd, Jeffrey M.; Rodríguez-Botigué, Laura; Ramachandran, Sohini; Hon, Lawrence; Brisbin, Abra; Lin, Alice A. (2011-03-29)."Hunter-gatherer genomic diversity suggests a southern African origin for modern humans".Proceedings of the National Academy of Sciences.108 (13):5154–5162.doi:10.1073/pnas.1017511108.ISSN 0027-8424.PMC 3069156.PMID 21383195.
  9. ^Scudellari, Megan (June 2012)."Sohini Ramachandran: Population Tracker".The Scientist Magazine®. Retrieved2022-04-17.
  10. ^Smith, Katherine F.; Goldberg, Michael; Rosenthal, Samantha; Carlson, Lynn; Chen, Jane; Chen, Cici; Ramachandran, Sohini (2014-12-06)."Global rise in human infectious disease outbreaks".Journal of the Royal Society Interface.11 (101): 20140950.doi:10.1098/rsif.2014.0950.PMC 4223919.PMID 25401184.
  11. ^Nakka, Priyanka; Raphael, Benjamin J; Ramachandran, Sohini (2016-10-01)."Gene and Network Analysis of Common Variants Reveals Novel Associations in Multiple Complex Diseases".Genetics.204 (2):783–798.doi:10.1534/genetics.116.188391.ISSN 1943-2631.PMC 5068862.PMID 27489002.
  12. ^Berman, Jessica (October 29, 2014). "Global Infection Outbreaks Rise over Past 30 Years".Voice of America News / FIND; Washington.
  13. ^Atkinson, Elizabeth Grace; Audesse, Amanda Jane; Palacios, Julia Adela; Bobo, Dean Michael; Webb, Ashley Elizabeth; Ramachandran, Sohini; Henn, Brenna Mariah (2018-09-06)."No Evidence for Recent Selection at FOXP2 among Diverse Human Populations".Cell.174 (6): 1424–1435.e15.doi:10.1016/j.cell.2018.06.048.ISSN 0092-8674.PMC 6128738.PMID 30078708.
  14. ^"Sohini Ramachandran, Ph.D."pew.org. August 23, 2012. Retrieved2022-01-13.
  15. ^"Eight Women Win Pew Scholarships in the Biomedical Sciences".Women in Academia Report; Bartonsville. July 3, 2012.
  16. ^"Sohini Ramchandran awarded Wriston Fellowship".CCMB | Brown University. Retrieved2022-04-17.
  17. ^Gimenes, Livia (2021-07-03)."Sohini Ramachandran Receives The Philip J. Bray Award For Excellence In Teaching In The Physical Sciences".awards.cs.brown.edu. Retrieved2022-04-17.
  18. ^"Two Brown researchers earn top White House award for early-career scientists".Brown University. Retrieved2022-01-13.
  19. ^Abbey Bigler and Talylor Walter (26 February 2020)."PECASE Honoree Sohini Ramachandran Studies the Genetic Foundations of Traits in Diverse Populations".NIGMS Biomedical Beat Blog. Retrieved2022-04-17.

External links

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External links

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