From 1996 until her retirement in 2014, she was Professor of musicology and Director of the Musicological Institute of theRuprecht-Karls-Universität Heidelberg. Leopold held numerous elective positions in the Academic Self-Government; from 2001 to 2007 she wasvice-rector for studies and teaching at Heidelberg University, where she was responsible for the conversion of courses to the BA/MA system and a sensible distribution concept for the newly introduced tuition fees. Leopold has been a member of theHeidelberg Academy of Sciences and Humanities since 1999.[2]
Leopold's research focuses on the history of music from the 16th to the 18th century and on the question of how text and music combine to form an individual organism. She has studied this in connection with the Italian language and emphasized interdisciplinary approaches. This is reflected above all in her contributions to thehistory of opera. Leopold has published numerous books on this subject, a complete account of the 17th century opera, and writings on the operas ofClaudio Monteverdi,Georg Friedrich Handel andWolfgang Amadeus Mozart. Further focal points arehistorically informed performance, the relationship between musical text and performance,aesthetics of music as well as questions of music historiography and the epochal classification of music. Since 2006 Leopold has been head of the research centre of the Südwestdeutsche Hofmusik of the Heidelberg Academy of Sciences.[2][3]
Parallel to her scientific career, Leopold develops extensive journalistic activities, as the communication of scientific findings to an interested public outside her peers is important to her. She moderates and writes broadcasts on topics from her specialist fields in broadcasting, has co-developed various radio formats, writes programme book texts and organises seminars and teacher training courses outside the university.[2]
Die Oper im 17. Jahrhundert (=Handbuch der musikalischen Gattungen. Vol. 11). Laaber Verlag, Laaber 2004,ISBN3-89007-134-1 (Unchanged special edition. (Geschichte der Oper. Vol. 1). ibid 2006,ISBN3-89007-658-0).
„Al modo d'Orfeo". Dichtung und Musik im italienischen Sologesang des frühen 17. Jahrhunderts (=Analecta Musicologica. Vol. 29). 2 volumes (vol. 1:Abhandlung.ISBN3-89007-277-1; vol. 2:Notenbeispiele und Katalog.ISBN3-89007-278-X). Laaber Verlag, Laaber 1995 (Zugleich: Berlin, Techn. Univ., Habil.-Schr.).
Stefano Landi. Beiträge zur Biographie. Untersuchungen zur weltlichen und geistlichen Vokalmusik (Hamburger Beiträge zur Musikwissenschaft. Vol. 17). 2 volume. Verlag der Musikalienhandlung Wagner, Hamburg 1976,ISBN3-921029-45-7 (Zugleich: Hamburg, Univ., Diss., 1975).
As editor:
with Sabine Ehrmann-Herfort:Migration und Identität. Wanderbewegungen und Kulturkontakte in der Musikgeschichte (Analecta Musicologica 49), Bärenreiter, Kassel etc. 2013,ISBN978-3-7618-2135-0.
with Norbert Greiner and Sara Springfeld:DasSonett und die Musik. Poetiken, Konjunkturen, Transformationen, Reflexionen. Beiträge zum interdisziplinären Symposium in Heidelberg vom 26. bis 28. September 2012, Winter, Heidelberg 2016,ISBN978-3-8253-6209-6.
Wolfgang Amadeus Mozart,Die Zauberflöte. Aria:Ein Mädchen oder Weibchen, facsimile and piano reduction, with an afterword by Silke Leopold, Bärenreiter, Kassel 2006ISBN978-3-7618-1775-9.
in collaboration with Jutta Schmoll-Barthel and Sara Jeffe:Mozart-Handbuch. Bärenreiter, Kassel u. a. 2005,ISBN3-7618-2021-6.
with Bärbel Pelker:Hofoper inSchwetzingen. Musik, Bühnenkunst, Architektur. Winter, Heidelberg 2004,ISBN3-8253-1524-X.
withThomas Betzwieser:Georg Joseph Vogler. Ein Mannheimer im europäischen Kontext (Quellen und Studien zur Geschichte der Mannheimer Hofkapelle. Vol. 7). Internationales Colloquium Heidelberg 1999. Lang, Frankfurt am Main etc. 2003,ISBN3-631-50095-5.
with Agnes Speck:Hysterie und Wahnsinn (Heidelberger Frauenstudien. Vol. 7). Wunderhorn, Heidelberg 2000,ISBN3-88423-174-X.
with Ullrich Scheideler:Oratorienführer. Metzler, Stuttgart etc. 2000,ISBN3-476-00977-7.
with Joachim Steinheuer:Claudio Monteverdi und die Folgen. Bericht über das Internationale Symposium Detmold 1993. Bärenreiter, Kassel etc. 1998,ISBN3-7618-1405-4.
with Robert Maschka:Who's who in der Oper. Bärenreiter, Kassel etc. 1997,ISBN3-7618-1268-X (Extended New Edition. ibid 2004,ISBN3-7618-1780-0).
Musikalische Metamorphosen. Formen und Geschichte der Bearbeitung (Bärenreiter Studienbücher zur Musik. Vol. 2). Bärenreiter, Kassel etc. 1992,ISBN3-7618-1051-2.
^abcdKuhl, Adrian (2018). ""Es darf auch schön klingen". Silke Leopold zum 70. Geburtstag".Musik in Baden-Württemberg. Jahrbuch 2017/18 (in German). Vol. 24. Stuttgart: J.B. Metzler Verlag. pp. 337, 339, 341, 342.ISBN978-3-476-04681-9.