![]() Fab fragment of sifalimumab bound to IFN-α2A. FromPDB:4ypg. | |
Monoclonal antibody | |
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Type | Whole antibody |
Source | Human |
Target | Interferon α |
Clinical data | |
ATC code |
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Identifiers | |
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ChemSpider |
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UNII | |
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Chemical and physical data | |
Formula | C6518H10008N1724O2032S38 |
Molar mass | 146252.08 g·mol−1 |
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Sifalimumab is a human monoclonal antibody designed for the treatment ofSLE,dermatomyositis, andpolymyositis.[1] It targets interferon a.[2]
Sifalimumab was developed byMedImmune; as of 2017 development had been terminated in favor of moving a competing internal product,anifrolumab, into Phase III trials.[3][4][5]
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