Seroprevalence is the number of persons in a population who test positive for a specific disease[1] based onserology (blood serum) specimens, often presented as a percent of the total specimens tested or as a proportion per 100,000 persons tested. As positively identifying the occurrence of disease is usually based upon the presence ofantibodies for that disease (especially with viral infections such asherpes simplex,HIV, andSARS-CoV-2), this number is not significant if thespecificity of the antibody is low.[citation needed]