Inanalytical chemistry,sample preparation (working-up) refers to the ways in which a sample is treated prior to its analyses. Preparation is a very important step in most analytical techniques, because the techniques are often not responsive to the analyte in itsin-situ form, or the results are distorted by interferingspecies. Sample preparation may involvedissolution,extraction,reaction with some chemical species,pulverizing, treatment with achelating agent (e.g.EDTA),masking,filtering,dilution,sub-sampling or many other techniques.Treatment is done to prepare the sample into a form ready for analysis by specified analytical equipment.Sample preparation could involve: crushing and dissolution, chemical digestion with acid or alkali, sample extraction, sample clean up and sample pre-concentration.

• "Sample Preparation". Retrieved2007-11-09.

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