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SYT2

From Wikipedia, the free encyclopedia
Protein-coding gene in the species Homo sapiens
SYT2
Identifiers
AliasesSYT2, SytII, CMS7, MYSPC, synaptotagmin 2, CMS7A, CMS7B
External IDsOMIM:600104;MGI:99666;HomoloGene:22516;GeneCards:SYT2;OMA:SYT2 - orthologs
Gene location (Human)
Chromosome 1 (human)
Chr.Chromosome 1 (human)[1]
Chromosome 1 (human)
Genomic location for SYT2
Genomic location for SYT2
Band1q32.1Start202,590,596bp[1]
End202,710,454bp[1]
Gene location (Mouse)
Chromosome 1 (mouse)
Chr.Chromosome 1 (mouse)[2]
Chromosome 1 (mouse)
Genomic location for SYT2
Genomic location for SYT2
Band1 E4|1 58.24 cMStart134,574,415bp[2]
End134,690,331bp[2]
RNA expression pattern
Bgee
HumanMouse (ortholog)
Top expressed in
  • pons

  • external globus pallidus

  • paraflocculus of cerebellum

  • cerebellar vermis

  • lateral nuclear group of thalamus

  • right hemisphere of cerebellum

  • superior vestibular nucleus

  • pars compacta

  • dorsal motor nucleus of vagus nerve

  • pars reticulata
Top expressed in
  • cerebellar cortex

  • inferior colliculi

  • medulla oblongata

  • deep cerebellar nuclei

  • pontine nuclei

  • medial vestibular nucleus

  • facial motor nucleus

  • anterior horn of spinal cord

  • cerebellar vermis

  • lobe of cerebellum
More reference expression data
BioGPS
More reference expression data
Gene ontology
Molecular function
Cellular component
Biological process
Sources:Amigo /QuickGO
Orthologs
SpeciesHumanMouse
Entrez

127833

20980

Ensembl

ENSG00000143858

ENSMUSG00000026452

UniProt

Q8N9I0

P46097

RefSeq (mRNA)

NM_001136504
NM_177402

NM_009307
NM_001355726

RefSeq (protein)

NP_001129976
NP_796376

NP_033333
NP_001342655

Location (UCSC)Chr 1: 202.59 – 202.71 MbChr 1: 134.57 – 134.69 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Synaptotagmin-2 is aprotein that in humans is encoded by theSYT2gene.[5][6]

References

[edit]
  1. ^abcGRCh38: Ensembl release 89: ENSG00000143858Ensembl, May 2017
  2. ^abcGRCm38: Ensembl release 89: ENSMUSG00000026452Ensembl, May 2017
  3. ^"Human PubMed Reference:".National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^"Mouse PubMed Reference:".National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^Jones JM, Popma SJ, Mizuta M, Seino S, Meisler MH (March 1995). "Synaptotagmin genes on mouse chromosomes 1, 7, and 10 and human chromosome 19".Mammalian Genome.6 (3):212–3.doi:10.1007/BF00293017.hdl:2027.42/47020.PMID 7749232.S2CID 24653745.
  6. ^"Entrez Gene: SYT2 synaptotagmin II".

Further reading

[edit]
Synaptic vesicle
SNARE
Q-SNARE
R-SNARE
Synaptotagmin
Other
COPI
COPII
RME/Clathrin
Caveolae
Other/ungrouped
Vesicle formation
Adaptor protein complex 1:
Adaptor protein complex 2:
Adaptor protein complex 3:
Adaptor protein complex 4:
BLOC-1:
BLOC-2:
BLOC-3:
Coats:
Small GTPase
Other
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