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Cationic amino acid transporter 3

From Wikipedia, the free encyclopedia
(Redirected fromSLC7A3)
Protein found in humans

SLC7A3
Identifiers
AliasesSLC7A3, ATRC3, CAT-3, CAT3, solute carrier family 7 member 3
External IDsOMIM:300443;MGI:1100521;HomoloGene:56382;GeneCards:SLC7A3;OMA:SLC7A3 - orthologs
Gene location (Human)
X chromosome (human)
Chr.X chromosome (human)[1]
X chromosome (human)
Genomic location for SLC7A3
Genomic location for SLC7A3
BandXq13.1Start70,925,579bp[1]
End70,931,125bp[1]
Gene location (Mouse)
X chromosome (mouse)
Chr.X chromosome (mouse)[2]
X chromosome (mouse)
Genomic location for SLC7A3
Genomic location for SLC7A3
BandX|X C3- DStart100,122,816bp[2]
End100,129,626bp[2]
RNA expression pattern
Bgee
HumanMouse (ortholog)
Top expressed in
  • tail of epididymis

  • gonad

  • tibialis anterior muscle

  • ventricular zone

  • thymus

  • ganglionic eminence

  • testicle

  • gastric mucosa

  • mucosa of ileum

  • body of uterus
Top expressed in
  • epiblast

  • embryo

  • dorsomedial hypothalamic nucleus

  • otic placode

  • ventral tegmental area

  • paraventricular nucleus of hypothalamus

  • central gray substance of midbrain

  • lateral hypothalamus

  • primitive streak

  • ventromedial nucleus
More reference expression data
BioGPS
n/a
Gene ontology
Molecular function
Cellular component
Biological process
Sources:Amigo /QuickGO
Orthologs
SpeciesHumanMouse
Entrez

84889

11989

Ensembl

ENSG00000165349

ENSMUSG00000031297

UniProt

Q8WY07

P70423

RefSeq (mRNA)

NM_032803
NM_001048164

NM_001301840
NM_007515

RefSeq (protein)

NP_001041629
NP_116192

NP_001288769
NP_031541

Location (UCSC)Chr X: 70.93 – 70.93 MbChr X: 100.12 – 100.13 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Cationic amino acid transporter 3 is aprotein that in humans is encoded by theSLC7A3gene.[5][6]

SLC7A3 is a member of the system y+ family of transporters characterized by sodium-independent transport of cationic amino acids.[supplied by OMIM][6]

See also

[edit]

References

[edit]
  1. ^abcGRCh38: Ensembl release 89: ENSG00000165349 –Ensembl, May 2017
  2. ^abcGRCm38: Ensembl release 89: ENSMUSG00000031297 –Ensembl, May 2017
  3. ^"Human PubMed Reference:".National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^"Mouse PubMed Reference:".National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^Vekony N, Wolf S, Boissel JP, Gnauert K, Closs EI (Oct 2001). "Human cationic amino acid transporter hCAT-3 is preferentially expressed in peripheral tissues".Biochemistry.40 (41):12387–94.doi:10.1021/bi011345c.PMID 11591158.
  6. ^ab"Entrez Gene: SLC7A3 solute carrier family 7 (cationic amino acid transporter, y+ system), member 3".

Further reading

[edit]

This article incorporates text from theUnited States National Library of Medicine, which is in thepublic domain.

By group
SLC1–10
(1):
(2):
(3):
(4):
(5):
(6):
(7):
(8):
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(10):
SLC11–20
(11):
(12):
(13):
(14):
(15):
(16):
(17):
(18):
(19):
(20):
SLC21–30
(21):
(22):
(23):
(24):
(25):
(26):
(27):
(28):
(29):
(30):
SLC31–40
(31):
(32):
(33):
(34):
(35):
(36):
(37):
(38):
(39):
(40):
SLC41–48
(41):
(42):
(43):
(44):
(45):
(46):
(47):
(48):
SLCO1–4
Symporter,Cotransporter
Antiporter (exchanger)


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