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SLC2A7

From Wikipedia, the free encyclopedia
Protein-coding gene in the species Homo sapiens
SLC2A7
Identifiers
AliasesSLC2A7, GLUT7, solute carrier family 2 member 7, GLUT-7, hGLUT7
External IDsOMIM:610371;MGI:3650865;HomoloGene:72470;GeneCards:SLC2A7;OMA:SLC2A7 - orthologs
Gene location (Human)
Chromosome 1 (human)
Chr.Chromosome 1 (human)[1]
Chromosome 1 (human)
Genomic location for SLC2A7
Genomic location for SLC2A7
Band1p36.23Start9,002,973bp[1]
End9,026,423bp[1]
Gene location (Mouse)
Chromosome 4 (mouse)
Chr.Chromosome 4 (mouse)[2]
Chromosome 4 (mouse)
Genomic location for SLC2A7
Genomic location for SLC2A7
Band4 E2|4Start150,233,429bp[2]
End150,252,939bp[2]
RNA expression pattern
Bgee
HumanMouse (ortholog)
Top expressed in
  • duodenum

  • colon

  • smooth muscle tissue
Top expressed in
  • jejunum

  • duodenum

  • blastocyst

  • yolk sac

  • embryo

  • embryo

  • colon

  • ileum

  • placenta

  • spleen
More reference expression data
BioGPS
n/a
Gene ontology
Molecular function
Cellular component
Biological process
Sources:Amigo /QuickGO
Orthologs
SpeciesHumanMouse
Entrez

155184

435818

Ensembl

ENSG00000197241

ENSMUSG00000062064

UniProt

Q6PXP3

P0C6A1

RefSeq (mRNA)

NM_207420

NM_001085529
NM_001368869

RefSeq (protein)

NP_997303

NP_001078998
NP_001355798

Location (UCSC)Chr 1: 9 – 9.03 MbChr 4: 150.23 – 150.25 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Solute carrier family 2, facilitated glucose transporter member 7 also known asglucose transporter 7 (GLUT7) is aprotein that in humans is encoded by theSLC2A7gene.[5][6]

SLC2A7 belongs to a family of transporters that catalyze the uptake of sugars through facilitated diffusion.[6] This family of transporters shows conservation of 12 transmembrane helices as well as functionally significant amino acid residues.[7]

See also

[edit]

References

[edit]
  1. ^abcGRCh38: Ensembl release 89: ENSG00000197241Ensembl, May 2017
  2. ^abcGRCm38: Ensembl release 89: ENSMUSG00000062064Ensembl, May 2017
  3. ^"Human PubMed Reference:".National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^"Mouse PubMed Reference:".National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^"Entrez Gene: solute carrier family 2 (facilitated glucose transporter)".
  6. ^abLi Q, Manolescu A, Ritzel M, Yao S, Slugoski M, Young JD, Chen XZ, Cheeseman CI (July 2004). "Cloning and functional characterization of the human GLUT7 isoform SLC2A7 from the small intestine".Am. J. Physiol. Gastrointest. Liver Physiol.287 (1): G236–42.doi:10.1152/ajpgi.00396.2003.PMID 15033637.S2CID 21269350.
  7. ^Joost HG, Thorens B (2001)."The extended GLUT-family of sugar/polyol transport facilitators: nomenclature, sequence characteristics, and potential function of its novel members (review)".Mol. Membr. Biol.18 (4):247–56.doi:10.1080/09687680110090456.PMID 11780753.S2CID 22667943.

Further reading

[edit]
By group
SLC1–10
(1):
(2):
(3):
(4):
(5):
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SLC11–20
(11):
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SLC21–30
(21):
(22):
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(24):
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(26):
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SLC31–40
(31):
(32):
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SLC41–48
(41):
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(46):
(47):
(48):
SLCO1–4
Symporter,Cotransporter
Antiporter (exchanger)


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