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Long-chain fatty acid transport protein 1

From Wikipedia, the free encyclopedia
(Redirected fromSLC27A1)
Protein-coding gene in the species Homo sapiens
SLC27A1
Identifiers
AliasesSLC27A1, ACSVL5, FATP, FATP1, FATP-1, solute carrier family 27 member 1
External IDsOMIM:600691;MGI:1347098;HomoloGene:8063;GeneCards:SLC27A1;OMA:SLC27A1 - orthologs
Gene location (Human)
Chromosome 19 (human)
Chr.Chromosome 19 (human)[1]
Chromosome 19 (human)
Genomic location for SLC27A1
Genomic location for SLC27A1
Band19p13.11Start17,468,769bp[1]
End17,506,168bp[1]
Gene location (Mouse)
Chromosome 8 (mouse)
Chr.Chromosome 8 (mouse)[2]
Chromosome 8 (mouse)
Genomic location for SLC27A1
Genomic location for SLC27A1
Band8|8 B3.3Start71,568,882bp[2]
End71,587,302bp[2]
RNA expression pattern
Bgee
HumanMouse (ortholog)
Top expressed in
  • apex of heart

  • pancreatic ductal cell

  • right hemisphere of cerebellum

  • muscle of thigh

  • left ovary

  • sural nerve

  • right ovary

  • C1 segment

  • right adrenal cortex

  • myocardium of left ventricle
Top expressed in
  • neural layer of retina

  • muscle of thigh

  • superior frontal gyrus

  • choroid plexus of fourth ventricle

  • lip

  • white adipose tissue

  • primary visual cortex

  • ventricular zone

  • subcutaneous adipose tissue

  • phalanx of third toe
More reference expression data
BioGPS
n/a
Gene ontology
Molecular function
Cellular component
Biological process
Sources:Amigo /QuickGO
Orthologs
SpeciesHumanMouse
Entrez

376497

26457

Ensembl

ENSG00000130304

ENSMUSG00000031808

UniProt

Q6PCB7

Q60714

RefSeq (mRNA)

NM_198580

NM_011977
NM_001357180
NM_001357181
NM_001357182

RefSeq (protein)

NP_940982

NP_036107
NP_001344109
NP_001344110
NP_001344111

Location (UCSC)Chr 19: 17.47 – 17.51 MbChr 8: 71.57 – 71.59 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Long-chain fatty acid transport protein 1 (FATP1) is aprotein that in humans is encoded by theSLC27A1gene.[5][6]

Structure

[edit]

TheSLC27A1 gene is located on the19th chromosome, with its specific location being 19p13.11. The gene contains 15exons.[6] SLC27A1 encodes a 71.1 kDa protein that is composed of 646 amino acids; 26 peptides have been observed throughmass spectrometry data.[7][8]

See also

[edit]

References

[edit]
  1. ^abcGRCh38: Ensembl release 89: ENSG00000130304 –Ensembl, May 2017
  2. ^abcGRCm38: Ensembl release 89: ENSMUSG00000031808 –Ensembl, May 2017
  3. ^"Human PubMed Reference:".National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^"Mouse PubMed Reference:".National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^Martin G, Nemoto M, Gelman L, Geffroy S, Najib J, Fruchart JC, Roevens P, de Martinville B, Deeb S, Auwerx J (June 2000)."The human fatty acid transport protein-1 (SLC27A1; FATP-1) cDNA and gene: organization, chromosomal localization, and expression".Genomics.66 (3):296–304.doi:10.1006/geno.2000.6191.PMID 10873384.
  6. ^ab"Entrez Gene: SLC27A1 solute carrier family 27 (fatty acid transporter), member 1".
  7. ^]Zong NC, Li H, Li H, Lam MP, Jimenez RC, Kim CS, Deng N, Kim AK, Choi JH, Zelaya I, Liem D, Meyer D, Odeberg J, Fang C, Lu HJ, Xu T, Weiss J, Duan H, Uhlen M, Yates JR, Apweiler R, Ge J, Hermjakob H, Ping P (October 2013)."Integration of cardiac proteome biology and medicine by a specialized knowledgebase".Circulation Research.113 (9):1043–53.doi:10.1161/CIRCRESAHA.113.301151.PMC 4076475.PMID 23965338.
  8. ^"Long-chain fatty acid transport protein 1".Cardiac Organellar Protein Atlas Knowledgebase (COPaKB).

Further reading

[edit]

This article incorporates text from theUnited States National Library of Medicine, which is in thepublic domain.

By group
SLC1–10
(1):
(2):
(3):
(4):
(5):
(6):
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SLC11–20
(11):
(12):
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(14):
(15):
(16):
(17):
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(19):
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SLC21–30
(21):
(22):
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(24):
(25):
(26):
(27):
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SLC31–40
(31):
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SLC41–48
(41):
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(46):
(47):
(48):
SLCO1–4
Symporter,Cotransporter
Antiporter (exchanger)


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