Genus of bacteria
Ruminococcus Clostridia .[ 2] Gram-positive gut microbes . One or more species in this genus are found in significant numbers in the humangut microbiota . The type species isR. flavefaciens . As usual, bacteria taxonomy is in flux, with Clostridia beingparaphyletic , and some erroneous members ofRuminococcus being reassigned to a new genusBlautia 16S rRNA gene sequences.[ 3]
One of the most highly cited papers involving the genusRuminococcus is a paper describinginterspecies hydrogen transfer betweenRuminococcus albus andWolinella succinogenes[ 4]
In 1972,Ruminococcus bromii was reportedly found in the human gut, which was the first of several species discovered.[ 5] colon .[ 6]
One study found thatR. albus ,R. callidus , andR. bromii are less abundant in people withinflammatory bowel disease .[ 7] Ruminococcus are also less abundant in patients withParkinson's disease [ 8] amyotrophic lateral sclerosis .[ 9] [ 10] R. gnavus is associated withCrohn's disease .[ 11]
The currently accepted taxonomy is based on theList of Prokaryotic names with Standing in Nomenclature (LPSN)[ 12] National Center for Biotechnology Information (NCBI)[ 2]
120 marker proteins basedGTDB 09-RS220[ 13] [ 14] [ 15] Ruminococcus R. champanellensis Chassard et al. 2012
R. callidus Holdeman & Moore 1974
R. flavefaciens Sijpesteijn 1948
^ "Ruminococcus" .^a b Sayers; et al."Ruminococcus" .National Center for Biotechnology Information (NCBI) taxonomy database. Retrieved2023-09-09 . ^ Liu C, Finegold SM, Song Y, Lawson PA (August 2008)."Reclassification of Clostridium coccoides, Ruminococcus hansenii, Ruminococcus hydrogenotrophicus, Ruminococcus luti, Ruminococcus productus and Ruminococcus schinkii as Blautia coccoides gen. nov., comb. nov., Blautia hansenii comb. nov., Blautia hydrogenotrophica comb. nov., Blautia luti comb. nov., Blautia producta comb. nov., Blautia schinkii comb. nov. and description of Blautia wexlerae sp. nov., isolated from human faeces" .International Journal of Systematic and Evolutionary Microbiology .58 (Pt 8). Society for General Microbiology:1896– 902.doi :10.1099/ijs.0.65208-0 PMID 18676476 . ^ Iannotti EL, Kafkewitz D, Wolin MJ, Bryant MP (June 1973)."Glucose fermentation products in Ruminococcus albus grown in continuous culture with Vibrio succinogenes: changes caused by interspecies transfer of H 2" .Journal of Bacteriology .114 (3):1231– 40.doi :10.1128/JB.114.3.1231-1240.1973 .PMC 285387 PMID 4351387 . ^ Rajilić-Stojanović M, de Vos WM (September 2014)."The first 1000 cultured species of the human gastrointestinal microbiota" .FEMS Microbiology Reviews .38 (5):996– 1047.doi :10.1111/1574-6976.12075 .PMC 4262072 PMID 24861948 . ^ Ze, Xiaolei; Duncan, Sylvia H.; Louis, Petra; Flint, Harry J. (2012)."Ruminococcus bromii is a keystone species for the degradation of resistant starch in the human colon" .The ISME Journal .6 (8):1535– 1543.Bibcode :2012ISMEJ...6.1535Z .doi :10.1038/ismej.2012.4 PMC 3400402 PMID 22343308 . ^ Nagao-Kitamoto H, Kamada N (February 2017)."Host-microbial Cross-talk in Inflammatory Bowel Disease" .Immune Network .17 (1):1– 12.doi :10.4110/in.2017.17.1.1 .PMC 5334117 PMID 28261015 . ^ Hill-Burns, EM; Debelius, JW; Morton, JT; Wissemann, WT; Lewis, MR; Wallen, ZD; Peddada, SD; Factor, SA; Molho, E; Zabetian, CP; Knight, R; Payami, H (May 2017)."Parkinson's disease and Parkinson's disease medications have distinct signatures of the gut microbiome" .Movement Disorders .32 (5):739– 749.doi :10.1002/mds.26942 .PMC 5469442 PMID 28195358 . ^ Brenner, D; Hiergeist, A; Adis, C; Mayer, B; Gessner, A; Ludolph, AC; Weishaupt, JH (Jan 2018). "The fecal microbiome of ALS patients".Neurobiol Aging .61 :132– 137.doi :10.1016/j.neurobiolaging.2017.09.023 .PMID 29065369 .S2CID 296116 . ^ Rowin, J; Xia, Y; Jung, B; Sun, J (Sep 2017)."Gut inflammation and dysbiosis in human motor neuron disease" .Physiol Rep .5 (18): e13443.doi :10.14814/phy2.13443 .PMC 5617930 PMID 28947596 . ^ Henke, Matthew T.; Kenny, Douglas J.; Cassilly, Chelsi D.; Vlamakis, Hera; Xavier, Ramnik J.; Clardy, Jon (2019-06-25)."Ruminococcus gnavus, a member of the human gut microbiome associated with Crohn's disease, produces an inflammatory polysaccharide" .Proceedings of the National Academy of Sciences .116 (26):12672– 12677.Bibcode :2019PNAS..11612672H .doi :10.1073/pnas.1904099116 ISSN 0027-8424 .PMC 6601261 PMID 31182571 . ^ A.C. Parte; et al."Ruminococcus" .List of Prokaryotic names with Standing in Nomenclature (LPSN). Retrieved2023-09-09 . ^ "GTDB release 09-RS220" .Genome Taxonomy Database . Retrieved10 May 2024 .^ "bac120_r220.sp_labels" .Genome Taxonomy Database . Retrieved10 May 2024 .^ "Taxon History" .Genome Taxonomy Database . Retrieved10 May 2024 .
