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Resocortol

From Wikipedia, the free encyclopedia
Chemical compound
Pharmaceutical compound
Resocortol
Clinical data
Other names11β,17α-Dihydroxy-21-methylpregn-4-ene-3,20-dione
Drug classCorticosteroid;Glucocorticoid
Identifiers
  • (8S,9S,10R,11S,13S,14S,17R)-11,17-Dihydroxy-10,13-dimethyl-17-propanoyl-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-3-one
CAS Number
PubChemCID
ChemSpider
UNII
KEGG
CompTox Dashboard(EPA)
Chemical and physical data
FormulaC22H32O4
Molar mass360.494 g·mol−1
3D model (JSmol)
  • CCC(=O)[C@]1(CC[C@@H]2[C@@]1(C[C@@H]([C@H]3[C@H]2CCC4=CC(=O)CC[C@]34C)O)C)O
  • InChI=1S/C22H32O4/c1-4-18(25)22(26)10-8-16-15-6-5-13-11-14(23)7-9-20(13,2)19(15)17(24)12-21(16,22)3/h11,15-17,19,24,26H,4-10,12H2,1-3H3/t15-,16-,17-,19+,20-,21-,22-/m0/s1
  • Key:HERCGHIBUWWDIX-CWNVBEKCSA-N

Resocortol is asyntheticglucocorticoidcorticosteroid which was never marketed.[1][2]

References

[edit]
  1. ^Challener CA (1 December 2001).Chiral Drugs. Wiley. p. 311.ISBN 978-0-566-08411-9.
  2. ^Coert A, Verheijen F, Horspool LJ, Mol JA (October 2004). "Aspects of pharmacodynamics and biotransformation of the glucocorticoid resocortol butyrate".Journal of Veterinary Pharmacology and Therapeutics.27 (5):309–15.doi:10.1111/j.1365-2885.2004.00583.x.PMID 15500568.
GRTooltip Glucocorticoid receptor
Agonists
Mixed
(SEGRMsTooltip Selective glucocorticoid receptor agonists)
Antagonists
Others
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