Movatterモバイル変換

Ranbezolid

From Wikipedia, the free encyclopedia

Chemical compound

Pharmaceutical compound

Ranbezolid
Clinical data

Other names	RBX-7644
Identifiers
IUPAC name N-{[(5S)-3-(3-Fluoro-4-{4-[(5-nitro-2-furyl)methyl]-1-piperazinyl}phenyl)-2-oxo-1,3-oxazolidin-5-yl]methyl}acetamide
CAS Number	392659-38-0
PubChemCID	496993
IUPHAR/BPS	11007
ChemSpider	435159
UNII	G3NB6JBL8A
ChEMBL	ChEMBL251384
CompTox Dashboard(EPA)	DTXSID701029733
Chemical and physical data
Formula	C₂₁H₂₄FN₅O₆
Molar mass	461.450 g·mol⁻¹
3D model (JSmol)	Interactive image
SMILES CC(=O)NC[C@H]1CN(C(=O)O1)c2ccc(N3CCN(Cc4oc(cc4)[N+](=O)[O-])CC3)c(F)c2
InChI InChI=1S/C21H24FN5O6/c1-14(28)23-11-17-13-26(21(29)33-17)15-2-4-19(18(22)10-15)25-8-6-24(7-9-25)12-16-3-5-20(32-16)27(30)31/h2-5,10,17H,6-9,11-13H2,1H3,(H,23,28)/t17-/m0/s1

Ranbezolid (RBx7644) is anoxazolidinone antibacterial. It competitively inhibitsmonoamine oxidase-A (MAO-A).^[1]

^Naruganahalli KS, Shirumalla RK, Bansal V, Gupta JB, Das B, Ray A (September 2006). "Ranbezolid, a novel oxazolidinone antibacterial: in vivo characterisation of monoamine oxidase inhibitory potential in conscious rats".European Journal of Pharmacology.545 (2–3):167–72.doi:10.1016/j.ejphar.2006.06.065.PMID 16899241.

-mycin (Streptomyces)	Streptomycin^# Dihydrostreptomycin Neomycin^# Framycetin Paromomycin^# Ribostamycin Kanamycin Amikacin^# Arbekacin Bekanamycin Dibekacin Tobramycin (+loteprednol) Spectinomycin^# Hygromycin B Totomycin Apramycin Nourseothricin
-micin (Micromonospora)	Gentamicin^# Netilmicin Sisomicin Micronomicin Plazomicin^# Isepamicin Verdamicin Astromicin
other	Butirosin

Tetracyclines	Doxycycline^# Chlortetracycline Clomocycline Demeclocycline Eravacycline Lymecycline Meclocycline^‡ Metacycline Minocycline Omadacycline Oxytetracycline Penimepicycline Rolitetracycline Sarecycline Tetracycline^#
Glycylcyclines	Tigecycline

Amphenicols	Chloramphenicol^# Azidamfenicol Thiamphenicol Florfenicol

Macrolides	Azithromycin^# Boromycin Carbomycin Carrimycin Clarithromycin^# Dirithromycin Erythromycin^# Flurithromycin Gamithromycin Josamycin Kitasamycin Midecamycin Miocamycin Nafithromycin Oleandomycin Rokitamycin Roxithromycin Solithromycin Spiramycin Telithromycin Tildipirosin Tilmicosin Troleandomycin Tulathromycin Tylosin Tylvalosin
Ketolides	Telithromycin^‡ Cethromycin Solithromycin^†
Lincosamides	Clindamycin^# Lincomycin Pirlimycin
Streptogramins	Pristinamycin (IA,IIA,IIB) NXL103 (Flopristin,Linopristin) Quinupristin/dalfopristin (Dalfopristin,Quinupristin) Streptogramin A Streptogramin B Virginiamycin (S1)

This systemicantibiotic-related article is astub. You can help Wikipedia byexpanding it.

Hidden categories: