Movatterモバイル変換

[0]ホーム
URL:

Jump to content
WikipediaThe Free Encyclopedia
Search

RALY

From Wikipedia, the free encyclopedia
Protein-coding gene in the species Homo sapiens
RALY
Available structures
PDBOrtholog search:PDBeRCSB
List of PDB id codes

1WF1

Identifiers
AliasesRALY, HNRPCL2, P542, RALY heterogeneous nuclear ribonucleoprotein
External IDsOMIM:614663;MGI:97850;HomoloGene:7216;GeneCards:RALY;OMA:RALY - orthologs
Gene location (Human)
Chromosome 20 (human)
Chr.Chromosome 20 (human)[1]
Chromosome 20 (human)
Genomic location for RALY
Genomic location for RALY
Band20q11.22Start33,993,646bp[1]
End34,108,308bp[1]
Gene location (Mouse)
Chromosome 2 (mouse)
Chr.Chromosome 2 (mouse)[2]
Chromosome 2 (mouse)
Genomic location for RALY
Genomic location for RALY
Band2 H1|2 76.83 cMStart154,633,016bp[2]
End154,709,181bp[2]
RNA expression pattern
Bgee
HumanMouse (ortholog)
Top expressed in
  • ganglionic eminence

  • granulocyte

  • ventricular zone

  • right lobe of thyroid gland

  • mucosa of transverse colon

  • left lobe of thyroid gland

  • left testis

  • right testis

  • ascending aorta

  • popliteal artery
Top expressed in
  • neural layer of retina

  • ventricular zone

  • yolk sac

  • granulocyte

  • lip

  • embryo

  • epiblast

  • tail of embryo

  • embryo

  • thymus
More reference expression data
BioGPS


More reference expression data
Gene ontology
Molecular function
Cellular component
Biological process
Sources:Amigo /QuickGO
Orthologs
SpeciesHumanMouse
Entrez

22913

19383

Ensembl

ENSG00000125970

ENSMUSG00000027593

UniProt

Q9UKM9

Q64012

RefSeq (mRNA)

NM_007367
NM_016732

NM_001139511
NM_001139512
NM_001139513
NM_023130

RefSeq (protein)

NP_031393
NP_057951

NP_001132983
NP_001132984
NP_001132985
NP_075619

Location (UCSC)Chr 20: 33.99 – 34.11 MbChr 2: 154.63 – 154.71 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

RNA-binding protein Raly is aprotein that in humans is encoded by theRALYgene.[5][6]

Ininfectious mononucleosis, anti-EBNA-1antibodies are produced which cross-react with multiple normal humanproteins. The cross-reactivity is due to anti-gly/ala antibodies that cross-react with host proteins containing configurations like those in the EBNA-1 repeat. One suchantigen is RALY which is a member of the heterogeneous nuclearribonucleoprotein gene family.[6]


References

[edit]
  1. ^abcGRCh38: Ensembl release 89: ENSG00000125970 –Ensembl, May 2017
  2. ^abcGRCm38: Ensembl release 89: ENSMUSG00000027593 –Ensembl, May 2017
  3. ^"Human PubMed Reference:".National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^"Mouse PubMed Reference:".National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^Khrebtukova I, Kuklin A, Woychik RP, Michaud EJ (Nov 1999)."Alternative processing of the human and mouse raly genes(1)".Biochim Biophys Acta.1447 (1):107–12.doi:10.1016/s0167-4781(99)00126-8.PMID 10500250.
  6. ^ab"Entrez Gene: RALY RNA binding protein, autoantigenic (hnRNP-associated with lethal yellow homolog (mouse))".

Further reading

[edit]
PDB gallery
  • 1wf1: Solution structure of RRM domain in RNA-binding protein NP_057951
    1wf1: Solution structure of RRM domain in RNA-binding protein NP_057951


Stub icon

This article on agene on humanchromosome 20 is astub. You can help Wikipedia byexpanding it.

Retrieved from "https://en.wikipedia.org/w/index.php?title=RALY&oldid=1116596029"
Categories:
Hidden categories:
[8]ページ先頭
©2009-2025 Movatter.jp