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Quinazosin

From Wikipedia, the free encyclopedia
Quinazosin
Names
Preferred IUPAC name
6,7-Dimethoxy-2-[4-(prop-2-en-1-yl)piperazin-1-yl]quinazolin-4-amine
Identifiers
3D model (JSmol)
ChemSpider
UNII
  • InChI=1S/C17H23N5O2/c1-4-5-21-6-8-22(9-7-21)17-19-13-11-15(24-3)14(23-2)10-12(13)16(18)20-17/h4,10-11H,1,5-9H2,2-3H3,(H2,18,19,20)
    Key: HSIPLPKNLDWHSE-UHFFFAOYSA-N
  • InChI=1/C17H23N5O2/c1-4-5-21-6-8-22(9-7-21)17-19-13-11-15(24-3)14(23-2)10-12(13)16(18)20-17/h4,10-11H,1,5-9H2,2-3H3,(H2,18,19,20)
    Key: HSIPLPKNLDWHSE-UHFFFAOYAT
  • COC1=C(C=C2C(=C1)C(=NC(=N2)N3CCN(CC3)CC=C)N)OC
Properties
C17H23N5O2
Molar mass329.404 g·mol−1
Except where otherwise noted, data are given for materials in theirstandard state (at 25 °C [77 °F], 100 kPa).
Chemical compound

Quinazosin is anantihypertensiveα1-adrenergic receptorantagonist.[1]

References

[edit]
  1. ^Martin, RA; Barsoum, NJ; Sturgess, JM; De La Iglesia, FA (1985). "Leukocyte and bone marrow effects of a thiomorpholine quinazosin antihypertensive agent".Toxicology and Applied Pharmacology.81 (1):166–73.Bibcode:1985ToxAP..81..166M.doi:10.1016/0041-008x(85)90131-0.PMID 3840293.


α1
Agonists
Antagonists
α2
Agonists
Antagonists
β
Agonists
Antagonists


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