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Clinical data | |
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AHFS/Drugs.com | International Drug Names |
Routes of administration | Oral |
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ECHA InfoCard | 100.000.397![]() |
Chemical and physical data | |
Formula | C15H24N4O2S2 |
Molar mass | 356.50 g·mol−1 |
3D model (JSmol) | |
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Prosultiamine (INN; also known asthiamine propyl disulfide orTPD; brand nameJubedel,) is adisulfidethiaminederivative discovered in garlic inJapan in the 1950s, and is similar toallithiamine. It was developed as a treatment forvitamin B1 deficiency.[1][2][3] It has improvedlipidsolubility relative to thiamine and is not rate-limited by dependency on intestinaltransporters for absorption, hence the reasoning for its development.[4][5]
It has been studied as a potential treatment for infection withhuman T-lymphotropic virus (HTLV), since it has been shown to reduce viral load and symptoms.[6]