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Propiverine

From Wikipedia, the free encyclopedia
Chemical compound
Pharmaceutical compound
Propiverine
Clinical data
AHFS/Drugs.comInternational Drug Names
ATC code
Legal status
Legal status
Pharmacokinetic data
Eliminationhalf-life20.1 h
Identifiers
  • 1-methylpiperidin-4-yl diphenyl(propoxy)acetate
CAS Number
PubChemCID
ChemSpider
UNII
CompTox Dashboard(EPA)
Chemical and physical data
FormulaC23H29NO3
Molar mass367.489 g·mol−1
3D model (JSmol)
  • CCCOC(C1=CC=CC=C1)(C2=CC=CC=C2)C(=O)OC3CCN(CC3)C
  • InChI=1S/C23H29NO3/c1-3-18-26-23(19-10-6-4-7-11-19,20-12-8-5-9-13-20)22(25)27-21-14-16-24(2)17-15-21/h4-13,21H,3,14-18H2,1-2H3 ☒N
  • Key:QPCVHQBVMYCJOM-UHFFFAOYSA-N ☒N
 ☒NcheckY (what is this?)  (verify)

Propiverine is ananticholinergic drug used for the treatment of urinary urgency, frequency and urge incontinence, all symptoms of overactive bladder syndrome.[2][3] It is amuscarinic antagonist.[4]

References

[edit]
  1. ^"Digestive and bladder health".Health Canada. 9 May 2018. Retrieved13 April 2024.
  2. ^McKeage K (January 2013). "Propiverine: a review of its use in the treatment of adults and children with overactive bladder associated with idiopathic or neurogenic detrusor overactivity, and in men with lower urinary tract symptoms".Clinical Drug Investigation.33 (1):71–91.doi:10.1007/s40261-012-0046-9.PMID 23288694.S2CID 3399082.
  3. ^Huang W, Zong H, Zhou X, Wang T, Zhang Y (December 2015)."Efficacy and Safety of Propiverine Hydrochloride for Overactive Bladder in Adult: a Systematic Review and Meta-analysis".The Indian Journal of Surgery.77 (Suppl 3):1369–1377.doi:10.1007/s12262-015-1264-1.PMC 4775592.PMID 27011567.
  4. ^BNF 61. London: British Medical Journal Group and Pharmaceutical Press. March 2011. p. 511.ISBN 978-0-85369-962-0.
Urologicals, including antispasmodics (G04B)
Acidifiers
Urinaryantispasmodics
(primarilyantimuscarinics)
Other urologicals
mAChRsTooltip Muscarinic acetylcholine receptors
Agonists
Antagonists
Precursors
(andprodrugs)


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