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Prifinium bromide

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Chemical compound

Pharmaceutical compound

Prifinium bromide
Clinical data


AHFS/Drugs.com	International Drug Names
ATC code	A03AB18 (WHO)
Identifiers
IUPAC name 3-(Diphenylmethylene)-1,1-diethyl-2-methylpyrrolidinium bromide
CAS Number	4630-95-9^N
PubChemCID	20749
ChemSpider	19537^Y
UNII	3B7O9ZC520
ChEMBL	ChEMBL1213353^Y
CompTox Dashboard(EPA)	DTXSID3023508
ECHA InfoCard	100.022.774
Chemical and physical data
Formula	C₂₂H₂₈BrN
Molar mass	386.377 g·mol⁻¹
InChI InChI=1S/C22H28N.BrH/c1-4-23(5-2)17-16-21(18(23)3)22(19-12-8-6-9-13-19)20-14-10-7-11-15-20;/h6-15,18H,4-5,16-17H2,1-3H3;1H/q+1;/p-1^Y Key:UCGJZJXOPSNTGZ-UHFFFAOYSA-M^Y
^NY (what is this?) (verify)

Prifinium bromide is a pharmaceutical drug used primarily in the treatment ofirritable bowel syndrome due to its action as ananticholinergic.^[1]

Prifinium bromide'smechanism of action is believed to be due to its activity as anantispasmodic agent.^[2]

Prifinium bromide is anantimuscarinic.^[3]

^Piai, Guido (1975). "[Prifinium bromide in the treatment of the irritable colon syndrome]".Gastroenterology.77 (3):500–502.doi:10.1016/0016-5085(79)90012-X.PMID 37142.
^Silber W (1979). "[Prifinium bromide-a new antispasmodic.]".South African Medical Journal.56 (24):1033–1034.PMID 45057.
^Magalini M, Monica F (June 1995). "[Use of prifinium bromide in endoscopic premedication. A double-blind controlled study vs hyoscine N-butylbromide]".Minerva Gastroenterologica e Dietologica.41 (2):197–202.PMID 7647144.

Tertiary amino group	Camylofin Dicycloverine Difemerine Dihexyverine Mebeverine Oxyphencyclimine Piperidolate Rociverine Trimebutine
Quaternary ammonium compounds	Benzilone Bevonium Diphemanil Fenpiverinium Glycopyrronium Hexocyclium Isopropamide Mepenzolate Methantheline Otilonium Oxyphenonium Penthienate Pipenzolate Poldine Prifinium Propantheline Tiemonium Timepidium Tridihexethyl