Pozzilli is an Italiancomune (municipality) of theProvince of Isernia, in the regionMolise, located about 50 kilometres (31 mi) west ofCampobasso and about 15 kilometres (9 mi) southwest ofIsernia.
Pozzilli is located on a valley below theMainarde mountain range, next to theAbruzzo, Lazio and Molise National Park. It is crossed by the river Rava and is few km far from the town ofVenafro. The industrial area extends into eastern plain and is part of the "Isernia-Venafro Industrial Consortium".[3]