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Pituicyte

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(Redirected fromPituicytes)
Glial cell of the pituitary gland

Pituicyte
Details
LocationPosterior pituitary
FunctionGlial cell
Identifiers
Latinpituicytus
NeuroLex IDsao1004082033
THH3.08.02.2.00040
FMA83503
Anatomical terms of microanatomy

Pituicytes areglial cells of theposterior pituitary. Their main role is to assist in the storage and release ofneurohypophysial hormones.[1]

Structure

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Pituicytes are located in the pars nervosa of the posterior pituitary and interspersed with unmyelinatedaxons andHerring bodies. They generally stain dark purple with anH&E stain and are among the easiest structures to identify in the region.[2][3] Pituicytes have an irregular and branched shape which resembles that of another type of glial cell: theastrocyte.[4] Like astrocytes, their cytoplasm presents specificintermediate filaments made up ofglial fibrillary acidic protein (GFAP).[5]

Function

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Pituicytes are similar to astrocytes, another type of glial cell. Their main role is to assist in the storage and release ofhormones of the posterior pituitary. Pituicytes surround axonal endings and regulate hormone secretion by releasing their processes from these endings.[1]

Clinical significance

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Pituicytomas are rare tumors that arise from pituicytes. They may be mistaken for the much more commonpituitary adenoma, as well ascraniopharyngioma andmeningioma. Symptoms from themass effect of the tumor usually include vision disorders, and less often headaches,hypopituitarism (decreased function of the pituitary gland), fatigue, and decreased libido.[6]

See also

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List of distinct cell types in the adult human body

References

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  1. ^abHatton, GI (September 1988)."Pituicytes, glia and control of terminal secretion"(PDF).The Journal of Experimental Biology.139:67–79.PMID 3062122.
  2. ^Histology image: 38_08 at the University of Oklahoma Health Sciences Center
  3. ^Histology image:14003loa fromVaughan, Deborah (2002).A Learning System in Histology: CD-ROM and Guide.Oxford University Press.ISBN 978-0195151732.
  4. ^Ross M, Pawlina W (2011).Histology: A Text and Atlas (6th ed.). Lippincott Williams & Wilkins. p. 751.ISBN 978-0-7817-7200-6.
  5. ^Wei, XY; Zhao, CH; Liu, YY; Wang, YZ; Ju, G (2009). "Immuohistochemical markers for pituicyte".Neuroscience Letters.465 (1):27–30.doi:10.1016/j.neulet.2009.06.059.PMID 19559073.S2CID 39871786.
  6. ^Covington, MF; Chin, SS; Osborn, AG (December 2011)."Pituicytoma, spindle cell oncocytoma, and granular cell tumor: clarification and meta-analysis of the world literature since 1893".American Journal of Neuroradiology.32 (11):2067–2072.doi:10.3174/ajnr.A2717.PMC 7964422.PMID 21960498.

External links

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Anatomy of theendocrine system
Pituitary gland
Anterior
Posterior
Thyroid
Parathyroid gland
Adrenal gland
Cortex
Medulla
Gonads
Islets of pancreas
Pineal gland
Other
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