Thephallotoxins consist of at least seven compounds, all of which are bicyclicheptapeptides (seven amino acids), isolated from the death cap mushroom(Amanita phalloides). They differ from the closely relatedamatoxins by being one residue smaller, both in the final product and the precursor protein.[1]
Phalloidin had been isolated in 1937 byFeodor Lynen,Heinrich Wieland's student and son-in-law, and Ulrich Wieland of theUniversity of Munich.[2][3] The remaining six areprophalloin,phalloin,phallisin,phallacidin,phallacin andphallisacin. Though highly toxic to liver cells, phallotoxins have since been found to have little contribution to the death cap's toxicity because they are not absorbed through the gut. Reports of phalloidin in the edible (and sought after)Blusher (Amanita rubescens)[4] have not been confirmed by later researchers[5]