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Peripolar cells are specializedepithelial cells. Peripolar cells are located withinBowman's capsule at itsvascular pole. These cells were discovered at thevascular pole of thesheepglomerulus. The cells contain numerouscytoplasmic granules. The granules in peripolar cells are secretory, and the cells show features of secretory epithelial cells, although no exocytosis was observed. By secreting specific molecules, they may influence the composition of the filtrate and the reabsorption processes in therenal tubules. There is also ongoing research that if it is part of thejuxtaglomerular apparatus (JGA). The number, size, and appearance ofperipolar cells can vary across different mammalian species.[1][2]