Clarkson was born on December 29, 1959,[1] inNew Orleans, Louisiana, the daughter ofJackie Clarkson (née Brechtel), a New Orleans politician and councilwoman, and Arthur "Buzz" Clarkson,[2] a school administrator who worked at theLouisiana State University School of Medicine.[3] Clarkson's maternal great-grandmother was aLithuanian-Jewish[4] immigrant who settled in New Orleans, while her maternal grandfather immigrated from Spain.[5] Her mother's ancestry also includes Irish and German, while Clarkson's father was of English, Scottish, and Welsh descent.[5]
Clarkson returned to Broadway in 1989 inEastern Standard, portraying aWall Street investment counselor whose brother (played byKevin Conroy) is diagnosed withAIDS; the play ran from January to March of that year.[11]
Clarkson has stated that in the early 1990s, she went through a turbulent period in her career and was unable to find significant work.[13] She had a small role inJumanji (1995)[14] before being cast in the independent dramaHigh Art (1998), portraying a drug-addictedGerman actress in New York City.[9] Her performance earned her anIndependent Spirit Award nomination forBest Supporting Actress.[15]
In 1998, Clarkson had a small role in the critically acclaimed independent romantic comedyPlaying by Heart, portraying a woman at a bar who listens to a false story told by a man (Dennis Quaid) as part of his improv class. In 1999, Clarkson appeared in a supporting role as an ailing wife of a prison warden inThe Green Mile, which was nominated for aScreen Actors Guild Award for Best Ensemble Cast.[15] The same year, she had a supporting part in the romantic comedySimply Irresistible (1999), followed by a supporting part inStanley Tucci's biopicJoe Gould's Secret (2000).[16] Next, she portrayed a single mother in the dramaThe Safety of Objects (2001), and had a supporting role oppositeJack Nicholson in theSean Penn-directed thrillerThe Pledge (2001), playing the mother of a murder victim.[17] She also had a leading role in the independenthorror filmWendigo (2001), directed byLarry Fessenden,[18] and in the comedyWelcome to Collinwood (2002).[19]Roger Ebert praised the performances in the former, noting: "The actors [inWendigo] have an unforced, natural quality that looks easy but is hard to do."[18] In 2001 she had a recurring role onFrasier as Claire French, who datedFrasier Crane played byKelsey Grammer.
Following these critical successes, Clarkson had a lead role oppositeKurt Russell in the sports docudramaMiracle (2004), about the U.S. hockey team defeating the heavily favored Soviets in the 1980 Olympics, and played the wife of a news correspondent (Robert Downey Jr.) inGeorge Clooney's historical dramaGood Night, and Good Luck (2005), about the conflict between journalistEdward R. Murrow andJoseph McCarthy.[26] She then starred as the wife of a Hollywood studio executive in the independent dramaThe Dying Gaul (2005).[27] 2006 saw the release ofThe Woods, a supernatural horror film shot in 2003[28] in which she portrayed the headmistress of a girls' boarding school. The same year, she portrayed Sadie Burke inAll the King's Men, set in her native New Orleans.[29]
In 2010, Clarkson appeared oppositeLeonardo DiCaprio in theMartin Scorsese-directed thrillerShutter Island, playing a woman escaped from a psychiatric institution.[34] Recounting being cast in the part, Clarkson said: "I got the call that every actor lives for. 'Patty, Martin Scorsese is thinking of casting you in his new movie.' And I do what I call the little 'Martin Scorsese dance' around my apartment. I think I was in my underwear or pajamas. It's a call you live for. Then I hear back, 'But it's just one scene.' So then I'm dancing a little lower. Then I hear, 'It's you and Leonardo DiCaprio in a cave,' and then I'm dancing again."[34] The film was a box office hit, and Scorsese's highest-grossing film at the time.[35]
Clarkson subsequently had roles in two independent films:Legendary andMain Street (both 2010), before appearing in two mainstream comedies directed byWill Gluck:Easy A (2010), as the mother of a troubled high school student (Emma Stone), and as the mother of an executive recruiter (Mila Kunis) inFriends with Benefits (2011).[36] She also appeared in the romantic dramaOne Day (2011) as the mother of a college student in Scotland (portrayed byJim Sturgess),[37] and guest-starred on two episodes of the comedy seriesParks and Recreation.[19] In 2013, she had a supporting role in the thrillerThe East (2013) as the leader of a private intelligence firm.[38]
She subsequently starred in the science fiction filmJonathan, involving two brothers who alternately share a single body,[47] and the psychological horror filmDelirium, which was released directly-to-DVD.[48] Clarkson starred oppositeAmy Adams in the psychological dramaminiseriesSharp Objects (2018), portraying the wealthy mother of an alcoholic reporter (Adams) investigating a murder in theirMissouri town.[49] For her performance in the series, Clarkson won a Golden Globe Award forBest Supporting Actress in a Series, Miniseries or Television Film.
In 2023, Clarkson assumed the lead role in the espionage thriller seriesGray, co-produced byAGC Television andLionsgate Films. The series chronicles CIA operative Cornelia Gray's return to her former life after two decades in hiding, amidst revelations of a mole within the spy network she once belonged to.[50][51]
Clarkson resides in New York City.[23] In 2007, she purchased a loft inGreenwich Village forUS$1.5million (equivalent to $2.3million in 2024).[53] She listed it for $2.5million (equivalent to $3.1million in 2024) in November 2018.[54] She has never married and has no children,[55] stating in a 2013 interview, "I've never wanted to marry, I've never wanted children—I was born without that gene."[56] Three of Clarkson's four sisters have children and she is very close to her nieces and nephews.[57] One of her nephews, Mac Alsfeld,[58] is an actor, writer and director.[59]
She made her film debut inThe Untouchables (1987), followed by a supporting role inThe Dead Pool (1988). She appeared in numerous supporting roles in such films asThe Green Mile (1999),The Pledge (2001),Far from Heaven (2002),Dogville (2003),The Station Agent (2003),Pieces of April (2003),Good Night, and Good Luck (2005),Lars and the Real Girl (2007), andElegy (2008). She also appeared in Woody Allen filmsVicky Cristina Barcelona (2008) andWhatever Works (2009). In 2010, Clarkson had a supporting role in the thrillerShutter Island, followed by roles in the comediesEasy A andFriends with Benefits. She portrayed Ava Paige inThe Maze Runner (2014) and its two sequels. In 2017, she co-starred in Sally Potter's dramaThe Party and guest-starred on the Netflix seriesHouse of Cards. She co-starred with Amy Adams on the HBO miniseriesSharp Objects in 2018.
^Wiater, Stanley; Golden, Christopher; Wagner, Hank (2006).The Complete Stephen King Universe: A Guide to the Worlds of Stephen King. New York: Macmillan. p. 190.ISBN978-0-312-32490-2.
^Woodard, Josef (November 1, 2007)."Lars and the Real Girl".The Santa Barbara Independent. Santa Barbara, California. Archived fromthe original on December 9, 2018. RetrievedDecember 9, 2018.
^Mathieson, Craig (March 18, 2024). "Past becomes present in a role Clarkson couldn't refuse - Thriller".The Sydney Morning Herald. Sydney, Australia. p. 6.