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| Papuloerythroderma of Ofuji | |
|---|---|
| Specialty | Dermatology  |
Papuloerythroderma of Ofuji is a rare disorder most commonly found in Japan, characterized by pruriticpapules that spare the skinfolds, producing bands of uninvolved cutis, creating the so-called deck-chair sign. Frequently there is associated blood eosinophilia. Skin biopsies reveal a dense lymphohistiocytic infiltrate,eosinophils in the papillary dermis, and increasedLangerhans cells (S-100 positive). Systemic steroids are the treatment of choice and may result in long-term remissions.[1]: 57 [2]
It was characterized in 1984.[3][4]
Use of PUVA in treatment has been described.[5]
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