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PX-2

From Wikipedia, the free encyclopedia
Chemical compound
Pharmaceutical compound
PX-2
Legal status
Legal status
Identifiers
  • (S)-N-(1-amino-1-oxo-3-phenylpropan-2-yl)-1-(5-fluoropentyl)-1H-indazole-3-carboxamide
CAS Number
ChemSpider
UNII
Chemical and physical data
FormulaC22H25FN4O2
Molar mass396.466 g·mol−1
3D model (JSmol)
  • O=C(N[C@@H](C(N)=O)CC1=CC=CC=C1)C2=NN(CCCCCF)C3=C2C=CC=C3
  • InChI=1S/C22H25FN4O2/c23-13-7-2-8-14-27-19-12-6-5-11-17(19)20(26-27)22(29)25-18(21(24)28)15-16-9-3-1-4-10-16/h1,3-6,9-12,18H,2,7-8,13-15H2,(H2,24,28)(H,25,29)/t18-/m1/s1
  • Key:OJTAHWMZBJRSIR-GOSISDBHSA-N

PX-2 (also known as5F-APP-PINACA,FU-PX andPPA(N)-2201) is anindazole-basedsynthetic cannabinoid that has been sold online as adesigner drug.[1][2][3] It contains aphenylalanine amino acid amide as part of its structure.

Legality

[edit]

Sweden's public health agency suggested classifying PX-2 as hazardous substance on November 10, 2014.[4]

PX-2 is listed in the Fifth Schedule of the Misuse of Drugs Act (MDA) and therefore illegal in Singapore as of May 2015.[5]

As of October 2015 PX-2 is a controlled substance in China.[6]

See also

[edit]

References

[edit]
  1. ^"PX 2". Cayman Chemical. Retrieved15 July 2015.
  2. ^Qian Z, Jia W, Li T, Hua Z, Liu C (January 2017). "Identification and analytical characterization of four synthetic cannabinoids ADB-BICA, NNL-1, NNL-2, and PPA(N)-2201".Drug Testing and Analysis.9 (1):51–60.doi:10.1002/dta.1990.PMID 27239006.
  3. ^Dahm P, Thomas A, Rothschild MA, Thevis M, Mercer-Chalmers-Bender K (July 2022)."Phase I-metabolism studies of the synthetic cannabinoids PX-1 and PX-2 using three different in vitro models".Forensic Toxicology.40 (2):244–262.doi:10.1007/s11419-021-00606-6.PMC 9715525.PMID 36454402.S2CID 245540105.
  4. ^"Cannabinoider föreslås bli klassade som hälsofarlig vara" [Cannabinoids are proposed to be classified as dangerous to health]. Folkhälsomyndigheten. Retrieved16 July 2015.
  5. ^"CNB NEWS RELEASE". Central Narcotics Bureau (CNB). 30 April 2015. Archived fromthe original on 15 July 2015. Retrieved24 July 2015.
  6. ^"关于印发《非药用类麻醉药品和精神药品列管办法》的通知" [On the issuance of non-pharmaceutical narcotic drugs and psychotropic substances listed in the notice] (in Chinese). China Food and Drug Administration. 27 September 2015. Archived fromthe original on 1 October 2015. Retrieved1 October 2015.
Phytocannabinoids
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